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Institute of Bioengineering



Prof. Dominique Barthes-Biesel & Dr Anne-Virginie Salsac, Fluid structure interactions of microcapsules in flow

Image: Dr Anne-Virginie Salsac & Prof. Dominique Barthes-Biesel
Dr Anne-Virginie Salsac & Prof. Dominique Barthes-Biesel

Date: 14 June 2013   Time: 11:30 - 12:30

Fluid structure interactions of microcapsules in flow

Prof. Dominique Barthes-Biesel
Dr Anne-Virginie Salsac

Bioengineering Department
Biomechanics and Biomedical Engineering (UMR CNRS 6600)
Université de Technologie de Compiegne
B.P. 20529, F60206 Compiegne, FRANCE

A capsule is a small liquid droplet enclosed by a thin membrane which has shear elasticity. Capsules are widely found in nature in forms of cells, eggs, seeds, etc. Artificial capsules, which can be fabricated by encapsulation, have numerous applications in food, cosmetic, textile, biomedical and pharmaceutical industries. For many situations in nature and industry, capsules are subjected to an external flow and the membranes bear viscous force. Although the capsule’s global motion can be observed, the detailed membrane stress and the internal and surrounding flow fields are very difficult to measure. However, they are critical information for many areas, and one important example is the rupture control of capsules in flow (e.g. capsule breakup for drug release, damage of artificial red blood cells during circulation). Accurate mechanical modelling can provide reliable and detailed information about capsule motion, membrane stress and flow field etc: it is thus serving as an essential component for the design and optimization of capsules. This talk will address the development of modelling and understanding the microcapsule dynamics in flow.

Biography: Professor Dominique Barthes-Biesel obtained her PhD from Stanford University in 1972, and subsequently joined faculty of Université de Technologie de Compiegne. She pioneered the rigorous research of capsule dynamics in viscous flow and published the first classical theory in this field in 1980, which has been widely used to analyse experimental results or to validate numerical models. Her group also developed the first numerical model of a capsule undergoing large deformation using the boundary integral method. Recently, her group created a new fluid structure coupling method based on boundary integrals for the fluid and on finite elements for the membrane. Professor Dominique Barthes-Biesel has served as an associate editor of the prestigious Journal of Fluid Mechanics since 2007, Vice Chair of World Council for Biomechanics since 2002, and committee member of International Union of Theoretical and Applied Mechanics since 2004.

Dr Anne-Virginie Salsac has been a researcher and group leader in CNRS 6600 and the Bioengineering Department Université de Technologie de Compiegne since 2007. She obtained her PhD in 2005 from University of California, San Diego (USA) and École Polytechnique (France) under a joint program. Her research is in the field of biofluids applied to vascular mechanics, microcirculation and biomedical engineering applications. Recently, her group invented a new technology to measure the mechanical properties of capsules/cells using combined experimental and numerical approaches.

Location:  The People's Palace PP1
Contact:  Dr Yi Sui