"Design of bioactive materials for tissue regeneration" By Prof Chang, Chinese Academy of Sciences
Date: 29 February 2016 Time: 15:00 - 16:00
Previsous studies have shown that the chemical composition and nano-structure are two factors which could affect cell behavior and bone regeneration. In our recent studies, we have designed and fabricated calcium phosphate and silicate based bioactive ceramics and composites, and found that some silicate based bioceramics have the potential to stimulate osteogenesis, and this effect is dependent on the chemical composition of the materials. Furthermore, some of the silicate bioceramics even showed the activity to stimulate angiogenesis in vitro and in vivo. In addition, our studies also showed that the surface nano/micro-structure also affected osteogenesis and angiogenesis. Further studies demonstrated that these kind of bioactive materials not only have the activity for hard tissue regeneration, but also have the potential for soft tissue regeneration. Our results suggest that ?tissue inducing biomaterials? with certain chemical composition and surface structure may be designed for tissue regeneration and engineering applications.
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