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IoB Seminar Series: Dr Jonathon Dawson, Clay: new opportunities for tissue engineering and biomaterial design

Image: Dr Jonathon Dawson
Dr Jonathon Dawson

Date: 28 June 2017   Time: 15:00 - 16:00

Clay nanoparticles offer interesting opportunities for biomaterial design and regenerative medicine that are only beginning to be explored. For example, certain clays are known for their ability to adsorb biological molecules due to the large and highly charged specific surface area of the nano-sized particles. We have investigated the potential to harness this sorptive capacity of clay in regenerative medicine. Self-assembling clay gels were observed to rapidly adsorb VEGF165 to promote an angiogenic response in local endothelial populations in vitro and in vivo and clay nanoparticle films and gels significantly enhance localised BMP2 osteoinduction in vitro and at ectopic sites in vivo. Such approaches provide exciting possibilities for the generation of developmentally potent microenvironments able to direct the growth and differentiation of stem/progenitor cell populations for tissue regeneration.

Location:  Seminar Room, 3rd floor Engineering Building, Mile End
Contact:  Dr Jonathon Dawson