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Institute of Bioengineering


Past Events

November 2020

  Wed 18 Nov 2020
  15:00 - 16:00
Image: Prof Hanna IsakssonMultiscale and multimodal assessment of bone damage, with Prof Hanna Isaksson, Lund University, Sweden
Multiscale and multimodal assessment of bone damage Abstract: Bone is a smart composite construction material, and a fascinating biological tissue. Its hierarchically optimized structure and unique composition results in a tissue that in a healthy state is able to withstand surprisingly high loads without fracturing. However, when affected by degenerative diseases, its strength and fracture resistance diminish substantially. Thus, understanding how bone fails and fractures as an organ requires...
  Wed 11 Nov 2020
  13:30 - 16:00
Image: Organ-on-a-chip network symposium - November
Keynote speaker: Dr Karl Koehler, Harvard Medical School REGISTRATION NOW OPEN: Programme: Chair: Adrian Biddle, QMUL 1.30pm: Abstract presentations (20 mins plus Q&A): Arunima Sengupta, ARTORG Organs-on-Chip Technologies, University of Bern, Switzerland, "Modelling chronic lung diseases in a bio-inspired breathing alveolus-on-chip model" Asli Akidil, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, "Development and application...

October 2020

  Wed 28 Oct 2020
  15:00 - 16:00
Image: Seminar 'Topological Evolution of Polymer Interfaces' with Edmondo M. Benetti, Swiss Federal Laboratories for Materials Science and Technology
Online Seminar
This week's seminar is 'Topological Evolution of Polymer Interfaces' with Dr Edmondo M. Benetti of the Polymer Surfaces Group, Department of Materials, ETH Zürich, Zürich, Switzerland & Swiss Federal Laboratories for Materials Science and Technology (EMPA), St. Gallen, Switzerland. Abstract: The application of cyclic polymers in surface functionalization enables an extremely broad modulation of interfacial physicochemical properties, surpassing the attractive characteristics provided by...
  Wed 14 Oct 2020
  13:30 - 16:00
Image: Organ on a chip network symposium - OctoberQueen Mary hosts new Organ-on-a-chip Research symposia
Online Symposium
Queen Mary University of London has launched a new e-symposia series with research presentations related to organ-on-a-chip and other predictive in vitro models. The symposia are part of the UK Organ-on-a-chip Technologies Network which is funded via the Technology Touching Life scheme and directed by Prof Hazel Screen and Prof Martin Knight, both bioengineers at Queen Mary. The next symposium takes place on 14th October, 1:30-4:00pm with an international keynote from Prof Gordana Vunjak...
  Wed 7 Oct 2020
  15:00 - 16:00
Image: Dr Michele ZagnoniIn vitro models of cellular function and disease using microfluidic technologies
Online Seminar
The Institute is delighted to welcome Dr Michele Zagnoni, Centre for Microsystems and Photonics, EEE Dept., University of Strathclyde, as part of the new Insitute of Bioengineering seminar series. This will take place online and details will be posted here prior to the event. Abstract: The talk will focus on a range of developed microfluidic bioassays that allow cell functionality and compound screening to be studied using in vitro human models of biological systems and disease. Examples...

July 2020

  Wed 22 Jul 2020
  13:00 - 16:00
Image: Centre for Predictive in vitro Models (CPM) Launch Symposium
MS Teams online
We are pleased to announce the virtual launch of the Centre for in vitro Predictive Models. To celebrate you are invited to on-line symposium on Wednesday 22 July, 1-4pm BST. Please join us for an afternoon of exciting talks focused on the development and application of advanced in vitro models in biomedical research. The symposium will include a keynote lecture from Prof. Jennifer Lewis, Harvard University, plus research presentations from leaders in the field at Queen Mary and rapid-fire short...
  Wed 15 Jul 2020
  13:00 - 15:00
Image: Queen Mary & Emulate Organs-on-Chips Centre Virtual Launch
online event
Join us at the virtual launch of the Queen Mary & Emulate Organs-on-Chips Centre, a new collaborative venture between Emulate, Inc. and Queen Mary University of London providing access to Emulate’s Organs-on-Chips platform to industry and academic members of the UK Organ-on-a-chip Technologies Network. The virtual launch event is free and open to all with advance registration. The programme includes opening remarks from Dr Alison Cave (Innovate UK) followed by an international keynote,...

June 2020

  Wed 24 Jun 2020
  15:00 - 16:30
Image: Professor Joseph MoranSeminar - On the Origins of Biological Metabolism, with Professor Joseph Moran
Online - please register at the link below
We welcome Professor Joseph Moran who will talk about the emergence of life, specifically biological metabolism, purely from a chemical systems perspective. About this Event: Biological metabolism exhibits signs that it may have started as a self-organized chemical system. The need for continuity between prebiotic chemistry and biochemistry mean that the two probably still resemble each other in key ways. Our aim is to infer the conditions that produced the initial self-organized system. To...
  Wed 17 Jun 2020
  15:00 - 16:30
Image: Prof. Francesco StellacciSeminar - Supramolecular Approaches to Design Novel Antivirals, with Professor Francesco Stellacci
Online - register at link below
We welcome Professor Francesco Stellacci, who pioneered much about the display of ligands on nanoparticles, presents a new approach to fighting viruses. Please register at the Eventbrite link below. Viral infections are among the main causes of death in the world. When prevention is not an option, antiviral drugs are the last resort to prevent the spread and the mortality of these infections. There are only a few effective drugs on the market, for the most part they prevent intracellular...
  Wed 10 Jun 2020
  15:00 - 16:30
Image: Professor Frank GuptonSeminar - Flow Chemistry Making Waves in the Pharmaceutical Industry, with Professor Frank Gupton, CEO of Medicines for All
Online Event
On Wed, 10th June, at 3pm we welcome Professor Frank Gupton, CEO of Medicines for All, who will share how they have achieved the impossible - drastically decreasing the optimised cost of generic drugs by using flow chemistry. Please register at the Eventbrite link below. Frank Gupton is a professor at Virginia Commonwealth University and holds joint appointments in the Departments of Chemistry and the Department of Chemical and Life Science Engineering. He is the Floyd D. Gottwald Chair...

April 2020

  Wed 22 Apr 2020
  13:00 - 18:00
Image: Conference: IoB Phase 2 event - our event has been postponed to autumn - details to follow
This event has been postponed to autumn - details to follow
As part of the Relaunch of the Institute of Bioengineering we would like to get Institute of Bioengineering affiliated students to do a 3MT preliminary round. Our hope is to relaunch the Institute of Bioengineering later this year in the autumn. Students will learn about presenting and we will all learn about their research, giving an overview of some of the activities in IoB. 3MT is a research communication competition where PhD researchers are challenged to give an engaging and...

March 2020

  Wed 25 Mar 2020
  15:00 - 16:00
Image: Dr Michele ZagnoniSeminar: This event has been cancelled until further notice. If you would like to be notified of the new date as soon as it is confirmed, please get in touch at the link below.
This event has been cancelled until further notice. If you would like to be notified of the new date as soon as it is confirmed, please get in touch.
Dr Michele Zagnoni, Centre for Microsystems and Photonics, EEE Dept., University of Strathclyde, presents ‘In vitro models of cellular function and disease using microfluidic technologies’. Abstract: The talk will focus on a range of developed microfluidic bioassays that allow cell functionality and compound screening to be studied using in vitro human models of biological systems and disease. Examples will be shown based on: human stem cell-derived neuronal network patterning and...
  Tue 10 Mar 2020
  15:00 - 17:00
Image:'Let's Talk Hearts' Barts Biomedical Research Centre
The Conference Room, Barts Biomedical Research Centre, 1st floor Idea Store, Whitechapel London, E1 1BU
'Let's Talk Hearts' is aimed at anyone with an interest in heart conditions. Let’s Talk Hearts Tuesday 10 March 2020, 3-5pm, in the conference room, 1st floor Idea Store Whitechapel London E1 1BU. Let's Talk Hearts is aimed at anyone with an interest in heart conditions. For more information and registration, please email:, or call 0757 2768 985. See also Let’s Talk Hearts website: The NIHR Biomedical Research Centre is a...

February 2020

  Wed 26 Feb 2020
  15:00 - 16:00
Image: Kristi L. KiickSeminar: Phase-separating (poly)peptides in the design of biomaterials, with Professor Kristi L. Kiick, University of Delaware
PP2 People's Palace, Mile End Campus, Queen Mary University of London
Professor Kristi L. Kiick, University of Delaware, Department of Materials Science and Engineering. Macromolecular structures that are capable of selectively and efficiently engaging cellular targets offer important approaches for mediating biological events and in the development of hybrid materials. We have employed a combination of biosynthetic tools, bioconjugation strategies, and biomimetic assembly in the design of multiple types of biopolymer conjugates of thermoresponsive (poly...
  Wed 19 Feb 2020
  15:00 - 16:00
Image: Prof Sergi Garcia-ManyesSeminar: The mechanical stability of proteins regulates their translocation rate into the cell nucleus, Prof Sergi Garcia-Manyes, King's College London
PP2 People's Palace, Mile End Campus, Queen Mary University of London
The mechanical stability of proteins regulates their translocation rate into the cell nucleus, with Prof Sergi Garcia-Manyes, King’s College London. Elvira Infante1†, Andrew Stannard1†, Stephanie J. Board1, Palma Rico-Lastres1, Elena Rostkova1, Amy E.M. Beedle1, Ainhoa Lezamiz1, Yong Jian Wang1, Samuel Gulaidi Breen1, Fani Panagaki1, Vinoth Sundar Rajan1, Catherine Shanahan2, Pere Roca-Cusachs3 and Sergi Garcia-Manyes1,4* 1 Department of Physics, Randall Centre for Cell and Molecular...
  Wed 12 Feb 2020
  15:00 - 16:00
Image: Dr Alexander GillettSeminar: 'Triplet formation in non-fullerene acceptor organic solar cells', with Dr Alexander Gillett, University of Cambridge
Lecture Theatre PP2, People's Palace, Mile End Campus
Abstract: The development of electron accepting materials that are not based on fullerene derivatives has been key to the recent resurgence of organic solar cells (OSCs), with power conversion efficiencies of 17% reported.(1) However, despite the rapid progress made, the voltage losses of OSCs associated with non-radiative (NR) recombination events is still significantly higher than rival inorganic technologies, such as perovskites.(2) Therefore, the future of OSCs depends on our ability to...
  Wed 5 Feb 2020
  15:00 - 16:00
Image: Dr Isabel PalaciosSeminar: 'Motion of cytoplasmic components and its impact on actin and microtubule organisation', with Dr Isabel Palacios, Queen Mary
Lecture Theatre PP2, People's Palace, Mile End Campus, Queen Mary University of London
The Institute of Bioengineering welcomes Dr Isabel Palacios, lecturer on the Nanchang Joint Programme at Queen Mary University of London and a visitor scientist at the University of Cambridge. Isabel has extensive research experience and has worked in various research positions at the University of Cambridge for over 12 years. Dr Palacios completed her PhD studies at the European Molecular Biology Laboratory (EMBL), Heidelberg, Germany. She has been successful in obtaining various grants from...

December 2019

  Wed 11 Dec 2019
  15:00 - 16:00
Image: Dr E. Ada Cavalcanti-AdamSeminar: Chemo-mechanical regulation of receptor-mediated cell adhesion, with Dr E. Ada Cavalcanti-Adam, Max Planck Institute for Medical Research & Heidelberg University
PP1 Lecture Theatre, People's Palace, Mile End Campus
Abstract: Cells live in a complex environment, which comprises mechanical and chemical cues and regulates cell adhesion-mediated responses such as migration, proliferation and differentiation. Different strategies for the delivery of adhesive ligands and growth factors on material surfaces, with the aim of enhancing cell adhesion forces and signalling, will be presented. The use of such materials in combination with biophysical methods to measure and perturb cell and molecular forces will be...

November 2019

  Tue 26 Nov 2019
  13:00 - 17:30
Image: Queen Mary University of London Imaging SymposiumThe Advanced Molecular Imaging Service - Queen Mary Imaging Symposium
Whitechapel Queen Mary BioEnterprises Innovation Centre (Clarke-Kennedy Lecture Theatre), 42 New Rd, Whitechapel, London E1 2AX
Registration is now open for the ‘QMUL Imaging Symposium’ 2019, an afternoon of short talks showcasing the research made possible by Queen Mary’s advanced imaging technologies at the Queen Mary BioEnterprises Innovation Centre. This will be followed by a drinks reception an the opportunity to meet the facility staff who can help access these tools for yourself. You’ll get to see what’s possible with the huge range of techniques already at your fingertips, including microPET/CT,...
  Wed 20 Nov 2019
  13:00 - 14:00
Image: Prof Sally Price, FRS'Can we predict how pharmaceuticals will crystallize?' with Professor Sally Price, FRS from University College London
Fogg Lecture Theatre, Mile End Campus, Queen Mary University of London
We have the great pleasure to host Professor Sally Price FRS from University College London, who will deliver the 2019 Dewar Lecture: “Can we predict how pharmaceuticals will crystallize?” SHORT BIOGRAPHY Professor Sally Price is a world-leading computational chemist with expertise in the area of organic crystallisation. Sally trained as a theoretical chemist at the University of Cambridge, specialising in deriving models of the forces between molecules from their wave functions. She...
  Wed 13 Nov 2019
  16:00 - 17:00
Image: Dr Periklis PantazisSeminar: Chemical and mechanical interrogation of biological systems … and beyond, with Dr Periklis Pantazis, Imperial College London
PP1 People's Palace, Mile End Campus, Queen Mary University of London
NOTE: this week's seminar starts later than usual - at 16:00 Abstract: In recent years, advances in imaging probes, microscopy techniques and bioinformatics image analysis have markedly expanded the imaging toolbox available to developmental biologists. Apart from conventional phenotypic studies, embryonic development is increasingly investigated in vivo with improved accuracy in time and space and more detailed quantitative analyses down to the single-cell level (reviewed in 1). To get...
  Wed 6 Nov 2019
  09:00 - 18:00
Image: FIRED-UP - Faculty Industry Research Engagement Day, Faculty of Science and Engineering
The Octagon, Queens' Building, Mile End Campus, Queen Mary University of London E1 4NS
The Faculty of Science and Engineering at Queen Mary University of London will be showcasing its research excellence to specially invited innovative and R&D oriented companies at the Faculty Industrial Research Engagement Day (FIRED-UP) on 6th November 2019. The MRI's Dr Ana Jorge Sobrido will be giving a talk on “New Sustainable Materials for Energy Storage and Conversion Technologies” You must register to attend this event at the link below. The event will: provide you with cutting...

October 2019

  Wed 30 Oct 2019
  15:00 - 16:00
Image: Dr Roisin Owens, University of CambridgeSeminar: 3D Bioelectronic models of human biology, with Dr Roisin M. Owens at the University of Cambridge
PP1 Lecture Theatre, People's Palace, Mile End Campus
In vitro models of biological systems are essential for our understanding of biological systems. In many cases where animal models have failed to translate to useful data for human diseases, physiologically relevant in vitro models can bridge the gap. Many difficulties exist in interfacing complex, 3D models with technology adapted for monitoring function. Polymeric electroactive materials and devices can bridge the gap between hard inflexible materials used for physical transducers and soft,...
  Fri 18 Oct 2019
  12:00 - 13:00
Image: Dr Shery HuangSeminar: Functional Biointerface Elements via Biofabrication, with Dr Yan Yan Shery Huang, University of Cambridge
SEMS Seminar Room, 3rd floor Engineering Building, Mile End Campus
'Functional Biointerface Elements via Biofabrication' Imagine in the future, bionic devices that can merge device and biology which can simulate the functions of biological matters, perform molecular sensing, or even replace or improve parts of the organ as smart implants? Such bionic devices could further our understanding in the living systems, and present major leaps in regenerative medicine. An ongoing research effort of Shery Huang’s Biointerface lab is to develop new biofabrication...
  Thu 17 Oct 2019
  14:00 - 15:00
Image: Seminar: Co-culture Systems in Biomaterial Research & Regenerative Medicine with Professor James Kirkpatrick
GO Jones Building, Room LG1, Mile End Campus, Queen Mary University of London
Abstract: Healing processes are a highly regulated series of biological activities in the so-called “regenerative niche” to restore structural and functional integrity, and involve the coordinated and sequential release of numerous biological signals from various cell types. Understanding these processes is a pre-requisite for progress in regenerative medicine. However, studying tissue reactions at the interface with biomaterials is complex and requires relevant cellular models. Our model...

September 2019

  Fri 20 Sep 2019
  09:00 - 18:00
Image: Biology Meets Physics SymposiumConference: Biology Meets Physics Symposium
The Great Hall, People's Palace, Queen Mary University of London
We are delighted to present Queen Mary University of London's all day ‘Biology Meets Physics Symposium’. This will be a truly multidisciplinary event that reaches across world leading research at Queen Mary's Material Research Institute; The Institute of Bioengineering; the School of Biological and Chemical Sciences & Barts and The London School of Medicine and Dentistry. This research event takes place in the historic People’s Palace inside the beautiful Grade II listed Great Hall, a...

August 2019

  Wed 14 Aug 2019
  11:00 - 12:00
Image: Dr Jaeyun KimSeminar: Functional Nanomaterials and Hydrogels for Immunotherapy and Biomimetics, with Dr Jaeyun Kim from Sungkyunkwan University (SKKU), South Korea.
2.03 Joseph Priestly Seminar Room, Joseph Priestly Building, Mile End Campus
Failures of the native immune system to eradicate tumors are mostly due to the immunosuppressive environments created by the tumor. In order to generate robust and durable antitumor adaptive immune responses, it is crucial to overcome the immunosuppressive environments that affect to the immune cells.

July 2019

  Tue 16 Jul 2019
  11:00 - 12:00
Image: Professor Torsten WagnerSeminar: Optoswitch: A new platform to combine different light-addressable technologies for Lab-on-a-chip applications
G.O. Jones Building Room 610, Queen Mary University of London, Mile End Campus
The Faculty of Science & Engineering are delighted to welcome to Queen Mary Professor Torsten Wagner, of the FH Aachen University of Applied Sciences, Germany. Professor Wagner's talk is 'Optoswitch: A new platform to combine different light-addressable technologies for Lab-on-a-chip applications' Abstract: Lab-on-a-Chip units control the fluidics pathway, manipulate samples and read-out sensor data on a single chip. Usually, they need sophisticated and complex structures, combined with a...
  Tue 16 Jul 2019
  14:00 - 17:00
Image: Stem cell in vitro models clubLondon cancer and stem cell in vitro models club
Perrin Lecture Theatre, Blizard Institute, 4 Newark Street, London, E1 2AT
You are invited to the London cancer and stem cell in vitro models club on Tuesday 16th July, 2019 at 2:00 - 5:00 pm. The event takes place in the Perrin LT, Blizard Institute and is followed by drinks in the Old Library, Garrod Building, from 5:00 – 6:00 pm. Programme: 2:00 pm – Dr Gehad Youssef, QMUL. ‘Identifying cancer stem cells in patient specimens through high-content imaging - biological insights and prognostic potential.’ 2:25 pm – Dr Eirini Velliou, University of...

June 2019

  Thu 27 Jun 2019
  13:00 - 18:00
Image: 1st Queen Mary 3Rs meeting1st Queen Mary 3Rs meeting - Innovations in Animal Welfare and Research Meeting
Innovations Centre, Clark Kennedy Lecture Theatre Blizard Institute
We are pleased to announce the 1st Queen Mary 3Rs meeting - Innovations in Animal Welfare and Research Meeting that will be held at the Innovations Centre, Clark Kennedy Lecture Theatre Blizard Institute on the afternoon of the 27th June. Queen Mary University London is fully committed to the key principles of the 3Rs for the use of animals in research. This meeting will be an opportunity to promote and discuss all the great 3Rs innovations that our staff has developed within the last year,...
  Thu 27 Jun 2019
  14:00 - 16:00
Image: 2019 Life Sciences Image Award Exhibition and Prize-giving Event
The Neuron Pod, Whitechapel - please enter via Blizard Reception
Please join us over refreshments to celebrate the fantastic array of images we have received this year! Thursday 27th June, 2-4pm (prize-giving 3:30pm), The Neuron Pod, Whitechapel. Register your place here: We look forward to seeing you there! Please feel free to forward to colleagues.

May 2019

  Wed 29 May 2019
  14:00 - 17:00
Image: Bioengineering on a ChipBioengineering on a Chip
RSM G41, Ground Floor, Royal School of Mines Building, Imperial College London, South Kensington
This event will provide a forum for research at the interface of microfluidics, lab/organ-on-chip and biosensors with a series of talks, posters, and networking. Special guests include Professor Hazel Screen, Director of the Organ-on-a-Chip network and Professor of Biomedical Engineering at Queen Mary University of London and Dr. Xize Niu, Associate Professor at the University of Southampton whose research focuses on developing wearable/portable chemical sensors for healthcare and...
  Wed 22 May 2019
  14:00 - 15:00
Image: Professor Min Wang Seminar: Electrospinning: Technologies and Applications in the Biomedical Field, with Professor Min Wang
Arts One Lecture Theatre, Mile End Campus, Queen Mary University of London
Electrospinning: Technologies and Applications in the Biomedical Field, with Min Wang PhD CSci CEng, Department of Mechanical Engineering, The University of Hong Kong Abstract Electrospinning is not new. But it has attracted great attention in the biomedical field since two decades ago thanks to the distinctive properties of electrospun nanofibrous structures. Therefore, publications on electrospinning and electrospun structures have been on the exponential increase over the past 20 years,...
  Wed 1 May 2019
  15:00 - 16:00
Image: Professor Daniel ElsonSeminar: Surgical Imaging and Biophotonics, with Professor Daniel Elson, Imperial College London
PP1 People's Palace, Mile End Campus, Queen Mary University of London
Light-based technologies such as florescence, multispectral and polarisation resolved imaging are opening up the possibility for in vivo tissue characterisation and image-guided surgery using live information feedback. Rather than relying on the naked eye or preoperative MRI or CT scan data, surgeons in the future operating theatre will see an augmented reality view of the margins of diseased tissues or tumours at the time of the surgery. For instance, polarimetry can be used for minimally...

April 2019

  Mon 8
 - Tue 9 Apr 2019
Image: Conference: Organ-on-a-Chip Learning & Collaborative and Event
Queen Mary University of London Graduate Centre, Mile End Campus, East London
This event provides a valuable opportunity for network members from academia, healthcare, industry and governance to take part in a range of talks, industry demonstrations, training sessions and network workshops. Programme The draft event programme can be found here and includes: Day 1: Research talks, industry demonstrations and collaboration sessions including training Day 2 (Optional): Public engagement planning: special opportunity to get involved in the development of our funded...
  Wed 3 Apr 2019
  15:00 - 16:00
Image: Dr Viji DraviamSeminar: Live-cell microscopy of microtubule mediated force generation in dividing human cells, with Dr Viji M. Draviam, Queen Mary University of London
PP1 People's Palace, Mile End Campus, Queen Mary University of London
By developing and employing high-resolution live-cell imaging techniques, Dr Draviam has significantly contributed to the molecular understanding of how microtubule-mediated forces ensure proper cell division. Microtubules capture chromosomes and pull them apart into two sets; simultaneously, microtubules rotate the mitotic spindle to dictate the plane of division. The group demonstrated that human chromosomes are captured along microtubule-walls and then brought to microtubule-ends, without...

March 2019

  Wed 20 Mar 2019
  15:00 - 16:00
Image: Prof. Jeremy C. HebdenSeminar: Development of diffuse optical tomography for imaging the newborn infant brain, with Prof. Jeremy C. Hebden
PP1 People's Palace, Mile End Campus, Queen Mary University of London
Abstract: The use of near-infrared light to interrogate biological tissues is attractive because light penetration into tissue is relatively high, and the absorption is sensitive to the oxygenation status of haemoglobin. However, light is very highly scattered in tissue, and consequently imaging requires new types of instruments and sophisticated image reconstruction techniques. Diffuse optical tomography (DOT), a 3D imaging methodology has emerged as an increasingly prevalent research tool,...

February 2019

  Wed 27 Feb 2019
  15:00 - 16:00
Image: Professor Michael DustinSeminar: Nanoscale analysis of immune cell communication, with Professor Michael L. Dustin
PP1 People's Palace, Mile End Campus, Queen Mary University of London
Professor Dustin was trained in Tim Springer’s lab at Harvard Medical School and Stuart Kornfeld’s lab at Washington University in St Louis. He started his Lab at Washington University in St Louis using supported lipids bilayers to study dynamics of the immunological synapse. Work at NYU School of Medicine focused on in vivo analysis of immune cell function in multiple tissues with a focus on tolerance, cancer and infection models. In Oxford he has focused on the immune T cell...
  Wed 20 Feb 2019
  12:00 - 13:00
Image: Lorenzo Albertazzi, Eindhoven UniversitySeminar: A super-resolved look at synthetic nanomaterials, with Professor Lorenzo Albertazzi, Eindhoven University
Engineering, Room 3.71, Mile End, Queen Mary University of London
'A super-resolved look at synthetic nanomaterials' Nanomaterials revolutionized the field of biomedicine introducing innovative approaches towards drug delivery, molecular imaging, regenerative medicine and biosensing. However, despite the large investments in nanotechnology the translation into clinical applications is still unsatisfactory. One of the main reasons is the lack of knowledge about the behavior of nanostructures in the biological environment that makes the rational design of...
  Wed 13 Feb 2019
  15:00 - 16:00
Image: Professor Xavier TrepatSeminar: Mechanobiology of epithelial growth and folding, with Professor Xavier Trepat, Institute for Bioengineering of Catalonia (IBEC), Barcelona
PP1 People's Palace, Mile End Campus, Queen Mary University of London
Abstract: Biological processes such as morphogenesis, tissue regeneration, and cancer invasion are driven by collective migration, division, and folding of epithelial tissues. Each of these functions is tightly regulated by mechanochemical networks and ultimately driven by physical forces. I will present maps of cell-cell and cell-extracellular matrix (ECM) forces during cell migration and division in a variety of epithelial models, from the expanding MDCK cluster to the regenerating zebrafish...

January 2019

  Wed 30 Jan 2019
  15:00 - 16:00
Image: Prof. Liam M GroverSeminar: Correcting aberrations in tissue formation using materials: From scarring to pathological ossification, with Professor Liam Grover
PP1 People's Palace, Mile End Campus, Queen Mary University of London
“Correcting aberrations in tissue formation using materials: From scarring to pathological ossification” with Professor Liam Grover, from the School of Chemical Engineering at the University of Birmingham. Localised changes in tissue structure can lead to a significant reduction in a tissue’s ability to function. Deposition of irregular arrays of collagen in the cornea, for example, result in reductions in transparency and sight loss. We are working on new ways to prevent and/or...
  Wed 16 Jan 2019
  15:00 - 16:00
Image: Dr Sam AuSeminar: Microfluidic Platforms for Investigating and Isolating Circulating Tumour Cell Clusters, with Dr Sam Au, Imperial College London
PP1 People's Palace, Mile End Campus, Queen Mary University of London
Multicellular aggregates of circulating tumour cells (CTC clusters) are potent initiators of distant organ metastases. Much is still unknown about their a) behaviour in the body, b) value as predictive/prognostic biomarkers and c) potential as therapeutic targets. The study of CTC clusters is hindered by challenges associated with isolating these rare aggregates from blood and observing their behaviour in physiological environments. Here I present microfluidic platforms designed to address both...

December 2018

  Thu 6 Dec 2018
  14:00 - 17:00
Image: London cancer and stem cell in vitro models club
Perrin Lecture Theatre, Blizard Institute, 4 Newark Street, London, E1 2AT
We will be holding our Winter edition of the London cancer and stem cell in vitro models club at the Blizard Institute from 2:00 – 5:00 pm on Thursday 6th December, followed by drinks from 5:00 – 6:00 pm. The programme will be followed by drinks in the Old Library, Garrod Building, from 5:00 – 6:00 pm. Programme: 2:00 pm – Dr Gary Warnes, QMUL. ‘Functional Biological Analysis of Live and Dead Cells by Flow Cytometry.’ 2:25 pm – Dr Alice Giustacchini, UCL. ‘Single-cell...
  Wed 5 Dec 2018
  15:00 - 16:00
Image: Dr Ciro ChiappiniSeminar: Functional nanomaterials for intracellular interaction to direct cell fate, with Dr Ciro Chiappini, King's College London
PP1 People's Palace, Mile End Campus, Queen Mary University of London
Engineering the cell-material interface to direct cell fate carries transformative potential for regenerative medicine, precision medicine and fundamental cell and molecular biology. Vertical arrays of nanowires and nanoneedles are rapidly emerging as promising biointerfaces capable of manipulating cells. Thanks to their high aspect ratio, nanoneedles interact simultaneously with multiple organelles within the cell, enabling gene delivery, intracellular sensing, and direct stimulation of...

November 2018

  Thu 29 Nov 2018
  12:30 - 13:30
Image: Professor Gorka OriveProgress in Tissue Regeneration and CNS Biomarkers with Professor Gorka Orive
SEMS Seminar Room, 3rd floor Engineering Building, Mile End
Abstract There are some drug delivery and regenerative medicine technologies that have seen several firsts in the last few years. In my conference I will summarize my experience in nano and microtechnologies including cell-laden hydrogels. In this approach, transplanted cells are protected from immune rejection by an artificial, semipermeable membrane, potentially allowing transplantation without the need for immunosuppression. Interestingly, the field of biological therapies constitutes a...
  Wed 28 Nov 2018
  09:00 - 18:30
Image: 13th UK Cancer Stem Cell SymposiumConference: 13th UK Cancer Stem Cell Symposium
The Bearsted Lecture Theatre, New Dental Hospital, Turner Street, Whitechapel, London E1 2AD
28th November 2018 -9.00am – 6.30pm The 13th in a series of annual meetings with guest speakers discussing ongoing developments in stem cell biology related to cancer. The meeting provides comprehensive updates on a range of cancer stem cell topics, reports recent research, and provides opportunities to network with colleagues who have active research interests in stem cells and cancer.
  Wed 21 Nov 2018
  15:00 - 16:00
Image: Mischa Zelzer Seminar: Surface-mediated self assembly of supramolecular structures - Teaching an old dog new tricks, with Mischa Zelzer, Assistant Professor in Biointerface and Materials Engineering at the University of Nottingham
PP1 People's Palace, Mile End Campus, Queen Mary University of London
The elegance of biological systems that exploit self-assembly of molecules into larger, functional structures continues to capture our imagination to develop new materials and technologies in biomaterial science, drug delivery and electronics to name but a few. This is notwithstanding the inherent challenges posed to control or direct the self-assembly process due the multitude of parameters (pH, temperature, concentration, solvent etc.) influencing the formation of supramolecular materials....

October 2018

  Wed 31 Oct 2018
  15:00 - 16:00
Image: Professor Rob KramsSeminar: A systems approach to the mechanobiology of blood vessels, with Professor Rob Krams, SEMS, Division of Bioengineering, Queen Mary University London
PP1 People's Palace, Mile End Campus, Queen Mary University of London
A surge of recent studies have highlighted the role of blood flow in determining plaque growth and plaque composition, both in animal studies and recent clinical trials. Despite these compelling data the underlying mechanism for flow-induced plaque formation is currently unknown. Blood flow is sensed by endothelial cells, and these cells react to blood flow by changing their gene signature. Initial studies showed that approximately 2000 genes are regulated by blood flow, distributed over 40...
  Wed 17 Oct 2018
  15:00 - 16:00
Image: Dr Sarah Stabenfeldt
Seminar: Regenerative Strategies for Neural Injury, with Dr Sarah Stabenfeldt from Arizona State University
PP1 People's Palace, Mile End Campus, Queen Mary University of London
Abstract: Over 1.7 million persons sustain a traumatic brain injury (TBI) in the U.S. alone. TBI is initiated by a mechanical injury and leads to a biochemical injury that is largely responsible for long-term functional and cognitive deficits. However, there are limited clinical therapeutic treatment options currently available for TBI patients where notably none address the underlying pathology and only alleviate secondary symptoms (i.e. edema, intracranial pressure, etc). This talk will focus...
  Wed 3 Oct 2018
  15:00 - 16:00
Image: Dr Adam PerrimanSeminar: New Directions in Regenerative Engineering, with Dr Adam Perriman, Reader in Biomaterials, University of Bristol
PP1 People's Palace, Mile End Campus, Queen Mary University of London
Reengineering cells to operate effectively in biological systems invariably involves the assembly of multiple components, which can only be integrated when compatible interfaces are built into the design. This can be achieved through the synthesis of hybrid materials comprising highly cooperative biological and synthetic constituents that can be used to amplify or attenuate cell-host tissue interactions. The systems methodology that underpins this design approach provides a gateway to the...

September 2018

  Wed 19 Sep 2018
  15:00 - 16:00
Image: Low-dimensional systems. Left: a model of the chromatophore vesicle form a purple bacterium. Centre: AFM image of an intact spherical vesicle. Right: a polymer brush microsystem designed to model transmembrane proton transportSeminar: Low-Dimensional Polymers, with Prof Graham Leggett, University of Sheffield
PP1 People's Palace, Mile End Campus, Queen Mary University of London
Many biological mechanisms can be thought of as being low-dimensional systems: their function is determined by molecular objects of reduced dimensionality. Bacterial photosynthesis is a very good example; the photosynthetic pathway is contained within nano-objects (vesicles) whose function is determined by the nanoscale organization of membrane proteins and by the number of those proteins and the ratio of different types of protein. Systems biology has provided computational models for studying...
  Thu 6
 - Fri 7 Sep 2018
Image: Organ on a Chip Network Launch EventOrgan on a Chip Network Launch Event
Day 1 - Imperial College, (event linked with BioMedEng18) & Day 2 - Queen Mary University of London, Graduate Centre)
Conference Day (9am–5pm: Imperial College, event linked with BioMedEng18) Network Inaugural lecture - Dr Geraldine Hamilton, President & Chief Scientific Officer, Emulate, Inc. Open session for organ-on-a-chip, in vitro model and other associated research talks 7th September: Network Activity Day (10am-4pm: QMUL, Graduate Centre) Funding prioritisation event (please help us define funding priorities for the network) * Networking and developing new collaborations * Shaping the...

July 2018

  Fri 6 Jul 2018
  14:15 - 17:00
Image: London cancer and stem cell in vitro models club London cancer and stem cell in vitro models club - summer meeting
Perrin Lecture Theatre, Blizard Institute, Queen Mary University of London, 4 Newark Street, London, E1 2AT
London cancer and stem cell in vitro models club - summer meeting Programme: 2:15 pm – Professor Hazel Screen, QMUL. ‘The Organ-on-a-Chip Technologies Network.’ 2:40 pm – Mr Matthew Dibble, QMUL. ‘Developing an Ovarian Cancer Model on-a-Chip.’ 3:05 pm – Tea and coffee in the Perrin foyer. 3:30 pm - Dr Jane Spencer-Fry, UPM Biofore. ‘Birch – the natural choice for 3D cell culture?’ 3:55 pm – Dr Ann-Marie Baker, QMUL. ‘Tracking tumour evolution using in situ...

June 2018

  Tue 26 Jun 2018
  15:00 - 16:00
Image: Professor Wei Sun Seminar: '3D bioprinted organs on a chip' with Professor Wei Sun, Professor of Mechanical Engineering at Drexel University, USA
Francis Bancroft Building, Room 326, Mile End Campus, Queen Mary University of London
3D Bio-Printing uses cells, biologics and/or biomaterials as building block to fabricate personalised 3D structures or functional in vitro biological models for regenerative medicine, disease study and drug discovery. This presentation will review some recent advances in 3D Bio-Printing and its applications for 'organ on a chip'. Biography: Professor Wei Sun is currently appointed Albert Soffa Chair Professor of Mechanical Engineering at Drexel University, USA, and National "Thousand-Talent...
  Tue 19 Jun 2018
  14:00 - 17:00
Image: Cell Dynamics and Cell Cycle Regulation, Fogg Building, QMULCell Dynamics and Cell Cycle Regulation Research Meeting
Fogg Building, Mile End Campus, Queen Mary University of London
We are expanding our series of biomedical research seminars into half-day research meetings. Cell Dynamics and Cell Cycle regulation talk - registration is free. Cancer Research Club is a free networking forum for Immunologists, Biochemists, Cell Biologists, Geneticists, Neuroscientists and Cancer researchers to discuss and present their findings at all levels of research from PhD to Professor. In addition, Cancer Research Club allows researchers to attend talks by leading international...

May 2018

  Thu 24 May 2018
  10:00 - 11:00
Image: Dr Lesley W. ChowSeminar: 'Functionalized polymer-based building blocks for constructing spatially organized biomaterials' with Dr Lesley W. Chow, Lehigh University, Bethlehem, USA
SEMS Seminar Room, 3/F, Engineering Building, Queen Mary University of London
The spatial organization of multiple components in biological tissues is intimately linked to the tissue’s function in the body. Disrupting this organization affects normal tissue function and properties, even if the overall composition remains the same. Inspired by native tissues, our lab focuses on developing strategies to combine and organize different components within a continuous construct to achieve new levels of functionality. The overarching goal is to create biomaterials that...
  Thu 10 May 2018
  13:00 - 14:00
Image: Prof Elizabeth TannerSeminar: 'Bioactive Biomaterials – where now?' with Professor Elizabeth Tanner OBE
SEMS Seminar Room, 3rd floor Engineering Building, Mile End
Seminar chaired by Professor Hazel Screen, Head of Bioengineering Divisional of SEMS BIOACTIVE BIOMATERIALS – where now? Elizabeth Tanner OBE, FREng, FRSE, PhD(Hon Caus), MA, DPhil Professor of Biomedical Materials, University of Glasgow, Glasgow Abstract Bioactive biomaterials started at Queen Mary University of London and are based on the concept that a material will function better in the body if its properties are closer to those of the natural material it is replacing. A range...

April 2018

  Wed 18 Apr 2018
  15:00 - 16:00
Image: Dr Madeline LancasterSeminar: Studying Human Brain Development and Evolution in Cerebral Organoids, with Dr Madeline Lancaster, MRC Laboratory for Molecular Biology, University of Cambridge
Arts One Lecture Theatre, Arts One, Mile End
Human brain development exhibits a number of unique characteristics, such as dramatic size expansion and variation in relative abundance of specific neuron populations. In an effort to better understand human brain development, we developed a human model system, called cerebral organoids. Cerebral organoids, or “mini-brains”, are 3D tissues generated from human pluripotent stem cells that allow modelling of brain development in vitro. We have been able to demonstrate that brain organoids are...
  Fri 6 Apr 2018
  13:00 - 14:00
Image: Dr Tatiana Vinardell Cartilage disease: connecting clinical to fundamental research with Dr Tatiana Vinardell, Equine Veterinary Medical Centre
The Scape, Room 0.14, Mile End Campus
Dr Vinardell will deliver an overview of her fundamental and clinical research. Her interests involve equine osteoarthritis, cartilage repair, regenerative medicine and tissue engineering. Orthopaedic injuries are a considerable economic burden to the equine industry, with athletic performance significantly impaired by pain and reduced mobility. This talk will give an overview of Dr Vinardell’s cartilage injury and osteoarthritis associated research, and its clinical applications. Surgical...

March 2018

  Wed 28 Mar 2018
  15:00 - 16:00
Image: Prof Christophe Moser   Seminar: Imaging with Multimode Fibers and Phase contrast imaging of the retina, with Prof. Christophe Moser, Laboratory of Applied Photonics Devices (LAPD), Lausanne, Switzerland
David Sizer Lecture Theatre, Bancroft Building, Mile End
Techniques for addressing image distortion through wavefront shaping and computational optics could pave the way for a new generation of extremely thin, high-resolution endoscopes for medical imaging. Because of the fibre’s ability to transmit multiple spatial modes of light simultaneously, MMFs could, in principle, replace the millimeters-thick bundles of fibers currently used in endoscopes with a single fiber only a few hundred microns thick. That, in turn, could potentially open up new,...
  Wed 14 Mar 2018
  15:00 - 15:30
Image: Dr Aleksandra Birn-JefferySeminar: Introductory Lecture: The neuromechanics of successful movement during non-steady tasks, with Dr Aleksandra Birn-Jeffery, Queen Mary
David Sizer Lecture Theatre, Bancroft Building, Mile End Campus
Humans and animals must regularly encounter and successfully deal with non-steady tasks, such as stepping over an object, and we usually accomplish this without falling or injuring ourselves. We still, however, know relatively little about the underlying control policies that regulate movement in such tasks. My research involves determining these control policies, and in particular, finding features of movement that can be used to identify the “safety” or “improvement” of locomotion....
  Wed 14 Mar 2018
  15:30 - 16:00
Image: Dr Thomas IskratschSeminar: POSTPONED - THIS INTRODUCTORY LECTURE WILL TAKE PLACE LATER IN THE YEAR: Rigidity sensing in the cardiovascular system, with Dr Thomas Iskratsch, QMUL
Mechanical properties are cues for many biological processes. We are investigating how these properties affect the cardiovascular health, thereby focusing on two cell types: cardiomyocytes and vascular smooth muscle cells (VSMCs). In the heart, changes to the extracellular matrix composition and cross-linking results in stiffening of the cellular microenvironment during development. However, myocardial infarction and cardiomyopathies lead to fibrosis and an even stiffer environment. Our work...
  Wed 7 Mar 2018
  16:00 - 17:00
Image: Dr Rodrigo S. LacruzIn and out with, and the ins and outs of, enamel matrix protein. The calcium control of enamel formation, with Dr Rodrigo S. Lacruz, Assistant Professor at New York University College of Dentistry
Sizer Lecture, Bancroft Building, QMUL, Mile End Road
The next lecture in this year’s Dental Physical Sciences Unit Research Seminar Series will be held on Wed 7th March starting at 4:00 pm. This will take place in the Sizer Lecture, Bancroft Building, QMUL, and is entitled “In and out with, and the ins and outs of, enamel matrix protein. The calcium control of enamel formation”. Our speaker is Dr Rodrigo S. Lacruz, Assistant Professor, at the Dept. of Basic Science and Craniofacial Biology New York University College of Dentistry and...
  Mon 5 Mar 2018
  15:00 - 16:00
Image: Dr Franck ArtznerSeminar: Bio-inspired peptidic nanotubes: from atomic structures to applications, with Dr Franck Artzner, Biomimetic Self-assemblies Group, Soft Matter Department, Institute of Physics - Rennes
LG01, People’s Palace, Mile End Campus
Two peptide nanotubes with well-defined organization resolved at molecularor atomic scale will be presented. Lanreotide is an octapeptide that self-assembles in water into highly monodisperse supramolecular nanotubes, the diameter and wall thickness of which are 244Å and 18Å respectively [Valery et al PNAS 2003]. These amyloid nanotubes can be used as a template to produce micron-long, bilayered silica nanotubes having a monodisperse diameter [Pouget et al, Nature Mat. 2007]. The diameter...

February 2018

  Thu 22
 - Fri 23 Feb 2018
Image: THE ROYAL MICROSCOPICAL SOCIETYConference: Microscopy Characterization of organic-inorganic Interfaces (see website link at the foot of the page below)
The People’s Palace, Mile End Campus, Queen Mary University of London
Microscopy Characterization of organic-inorganic Interfaces Day 1 - Main Conference • Lectures from experts in both materials science and life science microscopy from across the world covering a broad range of microscopy techniques: optical microscopy, scanning probe microscopy, scanning and transmission electron microscopy, correlative microscopy, etc • ‘Techno Bites’ from leading microscope manufacturers. • Trade exhibition and poster session providing great opportunities for...
  Wed 21 Feb 2018
  15:00 - 16:00
Image: Prof Xavier TrepatSeminar: SEMINAR CANCELLED - TO BE REARRANGED LATER IN THE YEAR Physical forces driving migration, division and folding in epithelial sheets, with Prof Xavier Trepat, Catalan Institution for Research and Advanced Studies (ICREA)

Biological processes such as morphogenesis, tissue regeneration, and cancer invasion are driven by collective migration, division, and folding of epithelial tissues. Each of these functions is tightly regulated by mechanochemical networks and ultimately driven by physical forces. I will present maps of cell-cell and cell-extracellular matrix (ECM) forces during cell migration and division in a variety of epithelial models, from the expanding MDCK cluster to the regenerating zebrafish epicardium....
  Wed 7 Feb 2018
  15:00 - 16:00
Image: Prof Hagan BayleySeminar: Synthetic tissues from communicating droplet networks, with Prof. Hagan Bayley University of Oxford
David Sizer Lecture Theatre, Bancroft Building, Mile End
Synthetic biology is being used to build devices through both top-down and bottom-up approaches. For example, genome engineering has been used to reprogram cells, and DNA origami has been used to produce a variety of nanodevices. While progress has been made on the bottom-up assembly of minimal cells, synthetic tissues have so far received limited attention. We have assembled networks of aqueous droplets joined by lipid bilayers. The droplets in the networks can communicate with each other and...

January 2018

  Wed 24 Jan 2018
  15:00 - 16:00
Image: Prof. Francisco GoycooleaSeminar: Oil-core chitosan based nanocapsules and their influence on 'life networks'
David Sizer Lecture Theatre, Bancroft Building, Mile End Campus
with Prof. Francisco Goycoolea, University of Leeds Chitosan-based nanocapsules (d.~200 nm; ?-potential~+60 mV) form by spontaneous emulsification and self assembly, under a phase separation-driven process. These “soft matter” systems are amenable to be loaded with lipophilic phytochemicals, namely capsaicin, cinnamaldehyde, curcumin, and flavonoids (namely quercetin and baicalein). Enhanced permeability, motility and cytoprotective effects, have all been evidenced on different mammalian...

December 2017

  Wed 6 Dec 2017
  15:00 - 16:00
Image: Prof Nick DonaldsonSeminar: Using integrated circuits for neural interfaces: is this realistic for chronic implants? Prof. Nick Donaldson, UCL
David Sizer Lecture Theatre, Bancroft Building, Mile End
As feature sizes of ICs get smaller year by year, the possibility of arranging one electrode per neuron rises: this is surely the ultimate for neural interfaces. Each electrode may need an associated amplifier, stimulator or multiplexing switches, and these may be adjacent to the electrode. We can therefore imagine using pads as electrodes and protecting the remainder of the surface with some suitable coating. But how long would such a device survive in the body? As a neuroprosthesis, it is...
  Fri 1 Dec 2017
  12:30 - 13:30
Seminar: “Exploiting induced chirality in DNA-templated supramolecular assemblies”, Dr Mathieu Surin from the University of Mons
The Fogg building Lecture Theatre
Mathieu Surin obtained a PhD from the University of Mons-Hainaut in 2005, working in the field of self-assembly and physical chemistry of conjugated polymers with Prof. Roberto Lazzaroni. In 2005, he was a Visiting Researcher at the University of...
  Fri 1 Dec 2017
  12:30 - 13:30
Seminar: “Exploiting induced chirality in DNA-templated supramolecular assemblies”, Dr Mathieu Surin from the University of Mons
The Fogg building Lecture Theatre
Mathieu Surin obtained a PhD from the University of Mons-Hainaut in 2005, working in the field of self-assembly and physical chemistry of conjugated polymers with Prof. Roberto Lazzaroni. In 2005, he was a Visiting Researcher at the University of...
  Fri 1 Dec 2017
  12:30 - 13:30
Image: Dr Mathieu SurinSeminar: Exploiting induced chirality in DNA-templated supramolecular assemblies, by Dr Mathieu Surin from the University of Mons
The Fogg building Lecture Theatre
Mathieu Surin obtained a PhD from the University of Mons-Hainaut in 2005, working in the field of self-assembly and physical chemistry of conjugated polymers with Prof. Roberto Lazzaroni. In 2005, he was a Visiting Researcher at the University of California, Santa Barbara in the laboratory of Prof. Alan Heeger. He then completed a post-doctoral year in the laboratory of Prof. Paolo Samorì at the Institute for Supramolecular Science and Engineering (ISIS) in Strasbourg, involved in the design of...

November 2017

  Wed 29 Nov 2017
  15:00 - 16:00
Image: Dr Patricia Horcajada Seminar: "Engineered-surface metal organic framework nanoparticles for drug delivery"
David Sizer LT
Joint Institute Seminar - Engineered-surface Metal-Organic framework nanoparticles for drug delivery. Dr Patricia Horcajada, IMDEA Energy, The involvement of Metal-Organic Frameworks (MOFs) in biomedical applications is currently one of the hot topics in the emerging field of hybrid porous solids. In particular, nanometric MOFs (nanMOFs) have recently attracted a great deal of attention owing to their large porosity and versatile composition, enabling one to...
  Wed 22 Nov 2017
  18:30 - 20:30
Image: Novel 3D bone regenerationSeminar: "Creating the Human" Seminars - Autumn/Winter 2017. The Bionic Body
Pathology Museum (3rd Floor Robin Brook Centre) QMUL School of Medicine and Dentistry St Bartholomew's Hospital Site West Smithfield, EC1A 7BE
Ticket only - Doors open 6:30pm for a 7PM start. There will be time to view the specimens "Creating the Human" Seminars - Autumn/Winter 2017. The Bionic Body Our "Creating the Human" Seminar Season focuses on how the human body can be created, re-created, misinterpreted and modified to devise our own, or others', physical and/or mental identities. Join Prof. Alvaro Mata (Biomedical Engineering & Biomaterials) for a fascinating and accessible lecture. He will talk about current research...
  Fri 17 Nov 2017
  12:00 - 13:00
Image: Prof Denitsa DochevaSeminar: IoB Seminar Series: Prof Denitsa Docheva, Mechanisms of tendon generation, degeneration and regeneration
SEMS Seminar Room, Engineering Building, Mile End
Tendon and ligament tissues are fascinating in their simplistic appearance of tissue architecture coupled with outstanding biomechanical properties. In the last decade, the mechanisms governing their development, degenerative disease progression and step-wise repair process are becoming better understood. In this talk, I will present an overview of our basic research work on these following points. (i) Tendon generation: I will discuss our finding on the role of growth and biomechanical factors...
  Tue 7 Nov 2017
  15:00 - 16:00
Image: Dr Deborah MasonSeminar: IoB Seminar Series: Dr Deborah Mason, Repurposing glutamate receptor antagonists to prevent and treat osteoarthritis: A voyage of discovery using cell, animal and human models
David Sizer Lecture Theatre, Bancroft Building, Mile End
This talk described how we have used animal (load-induced osteogenesis, antigen induced arthritis, menisectomy, anterior cruciate ligament rupture), cell (mechanically-loaded 3D osteocyte/osteoblastco-culture) and human models (high tibial osteotomy, total knee replacement, focal cartilage defects) to understand the role of glutamate signaling in the skeleton, and how this has revealed a potential therapeutic opportunity for prevention/treatment of osteoarthritis. Challenges of interdisciplinary...

October 2017

  Wed 25 Oct 2017
  15:00 - 16:00
Image: Prof Matthew GibsonSeminar: IoB Seminar Series: Prof. Matthew Gibson, Designing New Materials Inspired by Antifreeze Proteins for Cell Storage
David Sizer Lecture Theatre, Bancroft Building, Mile End Campus
Professor Matthew Gibson, University of Warwick, explains: All modern biotechnology, basic biology and regenerative medicine relies on the ability to store cells (or tissues) for subsequent usage. For example, most biomaterials research is conducted on freeze / thaw edimmortalized cells and recombinant protein expression relies on glycerol stocks of micro organisms. To enable the cells to be frozen large quantities of organic solvents such as DMSO must be added, and subsequently removed; These...
  Wed 11 Oct 2017
  15:00 - 16:00
Image: Prof Clemens KaminskiSeminar: IoB Seminar Series: Prof Clemens Kaminski, Optical super resolution microscopy of molecular mechanisms of disease
David Sizer Lecture Theatre, Bancroft Building, Mile End
The self-assembly of proteins into ordered macromolecular units is fundamental to a variety of diseases. For example, in Alzheimer’s Disease (AD) and Parkinson’s Disease (PD), proteins that are usually harmless are found to adopt aberrant shapes; one says they ‘misfold’. In the misfolded state the proteins are prone to aggregate into highly ordered, toxic structures, called protein amyloids and these make up the insoluble deposits found in the brains of patients suffering from these...

September 2017

  Wed 27 Sep 2017
  15:00 - 16:00
Image: Dr Daniela LoessnerSeminar: IoB Seminar Series: Dr Daniela Loessner, Bioengineered platforms to recreate tissue and tumour microenvironments
David Sizer Lecture Theatre, Bancroft Building, Mile End
Tissue engineering technology platforms have resulted in multi-disciplinary strategies to recreate a cell’s naturally occurring niche to study normal and pathological cell-cell and cell-niche interactions. Biofabrication techniques are used to design and produce scaffolds made of different biomaterials that represent tissue-like structures observed in real life. These biomimetic scaffolds model crucial properties of the extracellular matrix, provide mechanical support and anchorage to cells....

June 2017

  Wed 28 Jun 2017
  15:00 - 16:00
Image: Dr Jonathon DawsonSeminar: IoB Seminar Series: Dr Jonathon Dawson, Clay: new opportunities for tissue engineering and biomaterial design
Seminar Room, 3rd floor Engineering Building, Mile End
Clay nanoparticles offer interesting opportunities for biomaterial design and regenerative medicine that are only beginning to be explored. For example, certain clays are known for their ability to adsorb biological molecules due to the large and highly charged specific surface area of the nano-sized particles. We have investigated the potential to harness this sorptive capacity of clay in regenerative medicine. Self-assembling clay gels were observed to rapidly adsorb VEGF165 to promote an...

April 2017

  Wed 5 Apr 2017
  11:00 - 12:00
Image: Prof. Matthias LutolfSeminar: IoB Seminar Series: Prof. Matthias Lutolf, Engineering hydrogels to control stem cell self-organisation
Seminar Room, 3rd floor Engineering Building, Mile End
The earliest steps of development are characterized by cellular reorganization and differentiation within a three-dimensional (3D) microenvironment. This 3D context allows for a complex spatial interplay between biochemical and mechanical signals, and governs important cellular rearrangements leading to morphogenesis. In vitro approaches have attempted to capture key features of these processes, and it has now become possible to generate an increasing variety of self- organizing multicellular...

March 2017

  Wed 8 Mar 2017
  15:00 - 16:00
Image: Dr Eileen GentlemanSeminar: IoB Seminar Series: Dr Eileen Gentleman, Unravelling how bi-directional cell-biomaterial interactions direct stem cell fate in 3D
PP1 Lecture Theatre, People’s Palace, Mile End
Physical characteristics of a stem cell’s 3D environment, including its stiffness and degradability, are known to direct lineage specification. However, stem cells do not passively reside in their in vivo niche, but rather actively modify their local environment to suit their needs. In 3D hydrogels, which aim to replicate the in vivo environment, the role of such dynamic bi-directional interactions remains relatively unexplored. We created modifiable hydrogels and show that encapsulated human...

February 2017

  Wed 22 Feb 2017
  15:00 - 16:00
Image: Dr Ping Pui WongSeminar: IoB Seminar Series: Dr Ping Pui Wong, Improved treatment strategy for advanced breast cancer
PP1 Lecture Theatre, People’s Palace, Mile End
My research focuses on understanding the molecular basis of chemoresistance in cancer treatment. Although the anti-oestrogen tamoxifen treatment has improved survival for oestrogen receptor positive (ER+) breast cancer patients, eventual resistance is a common and devastating result for over 30% of patients, showing we must improve therapeutic strategies. Our preliminary studies suggest strongly that expression of MAGEA2 (Melanoma-Associated Antigen 2), and related members of this cancer...
  Wed 8 Feb 2017
  15:00 - 16:00
Image: Dr Philip BallSeminar: IoB Seminar Series: Dr Philip Ball, Why water is weird
PP1 Lecture Theatre, People’s Palace, Mile End
All life on Earth needs water to survive. But increasingly it seems that the characteristics that make water a solvent for life are also those that make it the weirdest of liquids. Some of these quirks of ‘life’s matrix’ are well understood; others are still being debated, sometimes furiously and controversially. I will explore what we do and don’t know about water, ending with a consideration both of how its behaviour in living cells can offer clues for new purification technologies...
  Wed 1 Feb 2017
  15:00 - 16:00
Image: Prof. Clark HungSeminar: IoB Seminar Series: Prof. Clark Hung, A Paradigm for Functional Tissue Engineering of Articular Cartilage
David Sizer Lecture Theatre, Francis Bancroft Building, Mile End
Articular cartilage is the specialized connective tissue that covers the ends of the bones that comprise our diarthrodial joints (e.g. knee and hip), and serves a critical load bearing and lubrication function. Absent of blood vessels, cartilage exhibits a poor intrinsic healing capacity after injury. The aim of our laboratory has been to engineer clinically-relevant articular cartilage grafts for repair of damaged and diseased joints. In this effort, several strategies have been employed to...

January 2017

  Wed 18 Jan 2017
  15:00 - 16:00
Image: Prof.Catherine PicartSeminar: IoB Seminar Series: Prof.Catherine Picart, Osteoinductive coatings to control bone tissue formation
People’s Palace, Mile End
Prof.Catherine Picart of the Institut Polytechniquede Grenoble presents: In vivo, cells are surrounded by an extra cellular matrix (ECM) which provide them with bioactive signals coming for the ECM proteins and growth factors. Presenting active biomolecules to cells using biomaterials as carriers enable them to mimic some aspects of the native ECM and to study cell signalling and tissue formation. Here, I will focus on the delivery of bioactive proteins, the bone morphogenetic proteins (BMPs)...

December 2016

  Wed 14 Dec 2016
  15:00 - 16:00
Image: Prof. Ehud GazitSeminar: IoB Seminar Series: Prof. Ehud Gazit, Self-assembly of Ultrashort Peptides and Metabolites: From Biology to Nanotechnology and Back
PP1 Lecture Theatre, People’s Palace, Mile End
Bio-inspired nanotechnology is a key front in the field of molecular self-assembly of new structures and composite families at the nano-scale. Concept and notions from biological self-assembly could allow the design and fabrication of nanomaterials, while molecular self-assembly paradigm could be applied to biological systems. Our work on the mechanis m of aromatic peptide self-assembly, lead to the discovery that the diphenylalanine recognition motif self-assembles into peptide nanotubes with a...
  Wed 7 Dec 2016
  15:00 - 16:00
Seminar: Prof. Jöns Hilborn (Uppsala University)

November 2016

  Wed 30 Nov 2016
  15:00 - 16:00
Image: Dr Gianni Dal NegroSeminar: IoB Seminar Series: Dr Gianni Dal Negro, Complex in Vitro models: challenges and expectations to fill the gaps
PP1 Lecture Theatre, People’s Palace, Mile End
The high attrition rate that the pharmaceutical industry is still facing indicates that the current tools for conducting our research too often fail in predicting the outcome in patients. Although considerable advances have been made in understanding differences and similarities between patients and pre- clinical animal species as models for human patho-physiology, in some cases we still fail in predicting results obtained in humans in particular when addressing challenges relating to human...
  Wed 16 Nov 2016
  15:00 - 16:00
Image: Dr Ben AlmquistSeminar: IoB Seminar Series: Dr Ben Almquist, Engineering the Interface with Biology: Adventures in Space and Time
PP1 Lecture Theatre, People’s Palace, Mile End
Recent advances in nanoscience have enabled us to create materials and devices that interact with biological systems across every relevant length scale, whether at the individual protein level or the hierarchical tissue level. In this talk I will explore how we can rationally design biotic-abiotic interfaces that seamlessly bridge the gap between synthetic devices and biological systems. I will begin by covering how inspiration from nature has allowed us to create biomimetic ‘inorganic...
  Wed 2 Nov 2016
  15:00 - 16:00
Image: Prof Sarah CartmellSeminar: IoB Seminar Series: Prof Sarah Cartmell, Advances in Orthopaedic Tissue Engineering: Bioreactor use, Electrical Stimulation and CT imaging Development
PP1 Lecture Theatre, People’s Palace, Mile End
The growing of new bone, cartilage, tendon and ligament tissue in vitro requires a variety of factors that need to be controlled and optimised. These factors (which include the cell type, scaffold type, growth factors / drugs and stimuli such as mechanical and electrical) require the use of a chamber to house the developing tissue and control the applied stimuli. The design and optimal use of several different types of these bioreactors will be discussed, in particular to address the nutrient...

October 2016

  Wed 19 Oct 2016
  15:00 - 16:00
Image: Prof Daniel KellySeminar: IoB Seminar Series: Prof Daniel Kelly, Cartilage, bone and joint regeneration using biomaterials, stem cells and 3D bioprinting
PP1 Lecture Theatre, People’s Palace, Mile End
Our musculoskeletal system has a limited capacity for repair. This has led to increased interest in the development of tissue engineering strategies for the regeneration of musculoskeletal tissues such as bone, ligament, tendon, meniscus and articular cartilage. This talk will review our attempts to use biomaterials and mesenchymal stem cells (MSCs) to tissue engineer functional articular cartilage and bone grafts for use in bone and joint regeneration. It will first outline our work developing...
  Wed 5 Oct 2016
  15:00 - 16:00
Image: Prof Ian HamleySeminar: IoB Seminar Series: Prof Ian Hamley, Peptides and Peptide Conjugates: From Self-assembly Towards Applications in Biomedicine
PP1 Lecture Theatre, People’s Palace, Mile End
Self-assembling peptides and their conjugates offer exceptional potential in nanomedicine. I will present some of our recent work on nanoscale assembled peptides and their conjugates, focussing on lipopeptides and PEG-peptide conjugates. PEGylation is an important technique in the development of conjugates for applications in therapeutics. It is found to greatly influence self- assembly of peptides and proteins - one example from our own work is a peptide which itself forms twisted fibrils but...

June 2016

  Sat 4 Jun 2016
  13:00 - 14:00
Image: Staying Strong - Joints in Space
FB 1.08, Bancroft Building, Mile end Campus
The golden rule of joint health is to exercise to help your tissues stay strong and healthy. The more you move, the less stiffness you will experience since exercise will help to protect your joints. But have you ever wondered what happens to your joints if you do too much or too little exercise? This sixty minute workshop presented by Dr Tina Chowdhury will discuss how exercise, diet and extreme environments such as space or “microgravity” effects joint health. By working with...
  Fri 3 Jun 2016
  13:00 - 14:00
Image: Seminar: "Molecular Biomechanics and Mechanobiology" by Prof. Cheng Zhu, Chair in Engineering at the Georgia Institute of Technology and Emory University.
PP1, People Palace, Mile End Campus
Molecular mechanics studies mechanics of biomolecules and uses mechanics to study biology at the molecular level. Molecular mechanobiology studies mechanotransduction at the molecular level. Mechanical factors can cause and/or regulate molecular deformation, conformational change, and receptor-ligand binding/unbinding. Information can be encoded and transferred through the molecular structure mechanically, and decoded remotely to be transduced into biological signal. In this talk, Dr. Cheng...
  Fri 3 Jun 2016
  15:00 - 16:00
PP1 People Palace
The current forms of cancer treatments (mainly surgery, chemotherapy, radiotherapy) are effective but often contribute to the complications and side effects. Patients may suffer during and after the cancer therapies. There are risks concerned with...

April 2016

  Wed 20 Apr 2016
  15:00 - 16:00
Image: Prof. HeeschenSeminar: "Cancer Stem Cells and Their Niche - New Opportunities for Bioengineering and Material Science", by Prof. Christopher Heeschen, Barts Cancer Institute
Arts One Lecture Theatre, Arts One, Mile End
Pancreatic cancer is hierarchical organised and cancer stem cells (CSC) represent the root driving tumour progression and metastasis. The tumour microenvironment further promotes these cell-intrinsic CSC phenotype including drug resistance and thus represents a critical factor of CSC responses to therapy in vivo. Currently, however, the cancer field is hampered by the lack of reliable and standardised human cancer models that comprehensively represent malignant cell responses within their...
  Thu 7 Apr 2016
  11:00 - 12:00
Image: Seminar: "Tissue engineering approaches for tendon regeneration: using synergies between biological, biochemical and physical stimulus" by Prof. Manuela Gomes, University of Minho, Portugal
SEMS Seminar room, Engineering Building, Mile End
Tendon tissue engineering (TE) requires tailoring scaffolds designs and properties to the anatomical and functional requirements of tendons located in different regions of the body. Cell sourcing is also of utmost importance as tendon cells are scarce. Recently, we have found that it is possible to direct the tenogenic differentiation of Amniotic fluid and Adipose tissue derived stem cells (hAFSCs and hASCs), and also that there are hASCs subpopulations that might be more prone to tenogenic...
  Wed 6 Apr 2016
  15:00 - 16:00
Image: Seminar: "Investigating cellular rigidity sensing with nanopillar arrays" by Dr Thomas Iskratsch, King's College London
PP1 Lecture Theatre, People’s Palace, Mile End Campus
The cellular microenvironment, which is defined by both chemical and physical parameters, guides cell migration, growth or differentiation during development to shape the heart and other organs. Conversely, injuries and diseases such as myocardial infarction, muscular dystrophies, or atherosclerosis result in a change of both molecular/chemical and physical aspects of the microenvironment. While chemical cues have well established roles in guiding processes such as migration or cell fate...

March 2016

  Tue 29 Mar 2016
  17:30 - 20:00
Image: Prof. IngberBioengineering the Human Body: Organ on Chips? by Prof. Donald Ingber; presented by David Ince
The Octagon, Queen Mary University, Mile End Campus
Bioengineering is set to change the future of medicine by applying leading edge engineering to solving health problems. We are proud to present a public lecture by the distinguished Harvard Professor Donald Ingber “The Next Technology Wave – Biologically Inspired Engineering”. He will talk about his work creating artificial human and animal organs on chips at the Wyss Institute at Harvard. This will revolutionise the practise of medicine by developing our ability to model and...
  Wed 16 Mar 2016
  10:00 - 11:00
Image: Assoc. Prof. RamamurthiSeminar: 'Biomimetic Approaches to Growing Biological Rubber Bands' by Assoc. Prof. Anand Ramamurthi, Cleveland Clinic
PP2, People Palace, Mile End
This seminar will summarize my laboratory’s efforts to develop matrix-engineering technologies directed at biomimetic regeneration and repair of elastic fibers and fiber networks. We seek to apply these methods to growing elastic tissues in vitro and for effecting regenerative matrix repair in tissues impaired by disruption of their structural extracellular matrix. Restoring the elastic matrix is crucial since its absence, malformation, or pathological disruption can adversely impact tissue...
  Wed 16 Mar 2016
  15:00 - 16:00
Image: Prof. ConnonSeminar: "Approaches to corneal tissue engineering: Top-down or bottom-up?" By Prof. Che Connon, Newcastle University
David Sizer Lecture Theatre, Bancroft Building, Mile End
Tissue engineering creates biological tissues that aim to improve the function of diseased or damaged tissues such as the cornea (the main refractive component of the eye). Traditional tissue engineering strategies employ a "top-down" approach, in which cells are seeded on a polymeric scaffold that they then populate and create the appropriate extracellular matrix (ECM) often with the aid of perfusion, growth factors and/or mechanical stimulation. However, in highly organised tissues, such as...
  Tue 15 Mar 2016
  12:00 - 13:00
Image: Assoc. Prof. MuraokaSeminar: 'Structured and Amphiphilic PEGs for Bio-related Chemistry' by Assoc. Prof. Takahiro Muraoka
Nanoforce seminar room, Mile End Campus
Poly(ethylene glycol) (PEG) is a versatile functional polyether with charge-free, flexible, water-soluble and thermo-responsive properties as well as high biocompatibility, which enrich the value of PEG in bio-related applications and materials development. Our group has been pursuing an investigation of the topological effects of PEG, where it was figured out as a significant example that triangle PEG forms self-assembly upon heating and shows suppression of protein thermal aggregation. The...
  Wed 9 Mar 2016
  15:00 - 16:00
Image: Dr DanoviSeminar: "HipSci Cell Phenotyping: building imaging platforms to characterise human induced pluripotent stem cell lines" By Dr Davide Danovi, King's College
Blizard Institute, Perrin Lecture Theatre, Whitechapel
Induced pluripotent stem cells (iPSCs) provide invaluable opportunities for future cell therapies as well as for studying human development, modelling diseases and discovering therapeutics. In order to realise the potential of iPSCs, it is crucial to comprehensively characterise cells generated from large cohorts of healthy and diseased individuals. The human iPSC initiative (HipSci) is assessing a large panel of cell lines to define cell phenotypes, dissect inter- and intra-line and donor...

February 2016

  Mon 29 Feb 2016
  15:00 - 16:00
Image: Prof ChangSeminar: "Design of bioactive materials for tissue regeneration" By Prof Chang, Chinese Academy of Sciences
PP1, People Palace, Mile End Campus
Previsous studies have shown that the chemical composition and nano-structure are two factors which could affect cell behavior and bone regeneration. In our recent studies, we have designed and fabricated calcium phosphate and silicate based bioactive ceramics and composites, and found that some silicate based bioceramics have the potential to stimulate osteogenesis, and this effect is dependent on the chemical composition of the materials. Furthermore, some of the silicate bioceramics even...
  Wed 17 Feb 2016
  15:00 - 16:00
Image: Dr NoroSeminar: Modelling at the appropriate lengthscale for industrial applications by Dr Massimo Noro, Unilever
David Sizer Lecture Theatre, Bancroft Building, Mile End
A large portion of the European manufacturing sector is based on complex liquid formulations, for example, in the area of home care and personal care products. Many of them are underpinned by similar liquid mesostructures. We need to choose the appropriate length-scale tools for the appropriate product mesostructure application. Coarse-grained mesoscale calculations insights to be gained, for example, on the mechanism of structure formation and on the interactions with surfaces of interest. ...
  Wed 3 Feb 2016
  15:00 - 16:00
Image: Prof. JerusalemSeminar: A unified mechanical approach for the modelling of traumatic brain injury
David Sizer Lecture Theatre, Bancroft Building, Mile End
Injuries of the CNS, i.e., TBIs and SCIs, are the current focus of large research campaigns. Experimentally, important advances have narrowed down the relation between impacts or blasts and functional deficits to a few key mechanisms, but the field remains vastly uncharted. To this end, numerical simulations have aimed at providing complementary information by mimicking TBI and SCI in silico. However, the link between mechanics and functional deficit is vastly ignored in almost all numerical...

January 2016

  Wed 20 Jan 2016
  15:00 - 16:00
Image: Seminar: "Cell polarisation guided by physical cues: from single cell to collective cell migration"
David Sizer Lecture Theatre, Bancroft Building, Mile End
Front-rear polarization, characterized by the establishment of cell protrusive polarity and directed migration is controlled by intrinsic cell properties but also by extracellular cues such as biochemical and physical cues. I will focus on the impact of mechanical cues on the establishment and maintenance of front-rear polarization from single cell to collective cell behaviors. Single cell polarization that precedes cell migration depends on a large variety of mechanochemical signals that...

December 2015

  Wed 16 Dec 2015
  13:00 - 14:00
Image: Prof. Morss ClyneSeminar: 'Endothelial cell mechanobiology in metabolic disease' by Prof. Alisa Morss Clyne, Drexel University
David Sizer LT, Bancroft Building, Mile End
In a healthy blood vessel, endothelial cells dynamically integrate biomechanical and biochemical signals from the flowing blood at their apical surface and the basement membrane at their basolateral surface. In metabolic diseases, changes in the biochemical environment may disturb endothelial cell response to mechanical forces, and the mechanical environment may affect biochemical kinetics. In this talk, I will present our research demonstrating that altered blood glucose, such as that...
  Wed 2 Dec 2015
  15:00 - 16:00
Image: Dr Claire HigginsSeminar: "Exploiting the inherent properties of dermal cells to engineer hair follicles" by Dr Claire Higgins, Imperial College London
PP1 Lecture Theatre, People's Palace, Mile End
During morphogenesis, hair follicles are formed as a result of interactions between mesenchymal and epithelial cell populations. A key component of these interactions is the dermal condensate which becomes known as the dermal papilla of the adult hair follicle. Just as the dermal condensate drives follicle development, the dermal papilla of the adult follicle is necessary for hair follicle cycling. Dermal papillae also maintain embryonic characteristics and when removed the follicle and...

November 2015

  Mon 30 Nov 2015
  12:45 - 13:45
Image: Dr Joe SwiftSeminar: "Mechanical and regulatory roles of the nuclear lamina" by Dr Joe Swift, University of Manchester
Derek Willoughby Lecture Theatre, Charterhouse Square
How cells receive and decipher mechanical inputs, by feeling the compliance of their surroundings or by being subject to deformation, is a key area of research in the field of mechanobiology. Cells in mature tissue must be appropriately regulated to meet the mechanical demands of their daily functions, with cells in stiff and mechanically loaded tissues requiring more robust cellular structures. I will discuss my work in the Discher laboratory, showing the composition of the nuclear lamina ? the...
  Wed 18 Nov 2015
  15:00 - 16:00
Image: Dr Remzi BecerSeminar: "Precision Macromolecular Synthesis and the GlycoCode" by Dr Remzi Becer, QMUL
PP1 Lecture Theatre, People's Palace, Mile End
Sequence controlled polymers have been attracting more and more attention to deliver the desired properties to the advanced materials by the help of their precisely controlled compositions and architectures.1 Development of various controlled radical polymerization techniques and ?click? reactions provide a sufficient platform to prepare functional polymers. Understanding the specific multivalent carbohydrate-protein interactions is crucial to determine the structure-property relationships and...
  Wed 11 Nov 2015
  14:40 - 15:40
Image: Prof. Paul MartinSeminar: "Investigating the roles of inflammation in skin repair and cancer" by Prof. Paul Martin, University of Bristol
Blizard Institute, Perrin Lecture Theatre, Whitechapel
  Wed 4 Nov 2015
  15:00 - 16:00
Image: Prof. James MooreSeminar: "Fluid Pumping and Mass Transfer in the Lymphatic System" by Prof. James Moore, Imperial College London
PP1 Lecture Theatre, People's Palace, Mile End
The lymphatic system has many recognized important roles in normal physiology and in a variety of disease conditions. In addition to returning fluid from interstitial tissue spaces to the blood circulation, it also serves as an important transport route for immune cells. Lymph nodes are important sites for cellular interactions involved in immunity, inflammation and fluid balance. Transport phenomena and/or breakdowns in lymphatic system performance are crucial, or at least involved in,...

October 2015

  Wed 21 Oct 2015
  15:00 - 16:00
Image: Seminar: Materials for the delivery of cells and drugs for regenerative medicine applications.
People's Palace, PP1 Theatre, Mile End
Professor Shakesheff is Director of the UK Regenerative Medicine Platform Hub for Acellular Technologies and will be presenting a variety of polymer-based materials that enhance the presentation of cells and molecules at intended sites of tissue repair. Regenerative medicine presents new and interesting problems in the design of materials for use in patients. The material needs to become incorporated into the newly formed tissues whilst creating the optimal mechanical environment. The Nottingham...

April 2015

  Thu 30 Apr 2015
  15:00 - 17:00
Image: Seminar: Assoc. Prof. Ben Corry. Simulation studies of biological and synthetic ion channels: from drug targets to water filtration technology
PP2 Lecture Theatre, The People's Palace, Mile End.
Biological ion channels are responsible for diverse range of activities including conducting nerve impulses, cell volume regulation and sensory transduction. This talk will demonstrate how we have been using molecular dynamics simulations to understand how sodium selective ion channels achieve their function at a molecular level and how this information is being used to develop new drugs for treating chronic pain. In addition we will show how the characteristics of biological pores can be copied...
  Wed 29 Apr 2015
  15:00 - 17:00
Image: Geoff McLarenSeminar: Geoff McGrath, McLaren Applied Technologies. Data-driven design. How innovation goes beyond the race track to deliver high performance in our lives
GO Jones Lecture Theatre, Mile End
Geoff will talk about how McLaren apply technology to deliver high performance in racing and how the ethos translates to other fields from elite sports to healthcare. A central theme will be the power of convergence of real-time data management, predictive analytics and simulation to deliver high-performance product and process design. Examples will be drawn from wide ranging industrial sectors where a combination of a different approach to design and a culture of innovation have delivered...
  Wed 22 Apr 2015
  15:00 - 17:00
Image: Dr. Christinna GewinnerSeminar: Dr Christinna Gewinner. Requirement for primed residues in the substrate phosphorylation motif of receptor tyrosine and non-receptor tyrosine kinases.
Derek Willoughby Lecture Theatre, John Vane Science Centre, Charterhouse Square.
Protein-tyrosine kinase inhibitors have been approved for treating a wide range of cancers. A detailed knowledge of protein-Tyr kinase signalling networks is needed to provide a logic for selecting drug combinations that are likely to be effective. However, one aspect of protein kinase biology that remains poorly understood is how kinases achieve specificity for their target substrates. Here, we have adapted a new positional scanning peptide library approach to address the substrate specificity...
  Wed 15 Apr 2015
  15:00 - 17:00
Image: Seminar: Dr Martin Goldberg.Communication across the Nuclear Envelope
Fogg Lecture Theatre. Fogg Building, Mile End.
The nuclear envelope (NE) is a double membrane system separating nucleus and cytoplasm. There are two connectivities across it: (1) Nuclear Pore Complexes (NPCs) provide aqueous channels to selectively facilitate transfer of soluble molecules; (2) the LINC complex links nucleoskeleton to cytoskeleton. NPCs are formed when inner and outer nuclear membranes fuse. There is a massive protein structure in the resulting pore, consisting of a scaffold with peripheral cytoplasmic filaments and...
  Wed 1 Apr 2015
  15:00 - 17:00
Image: Prof. Richard OreffoSeminar: Prof. Richard Oreffo. Bridging the gap - harnessing skeletal stem cells, nanotopography and environmental niches for bone repair.
David Sizer & DS Foyer, Bancroft Building, Mile End.
Medical advances have led to a welcome increase in world population demographics. However, increased aging populations pose new challenges and emphasize the need for innovative approaches to augment and repair tissue lost through trauma or disease. We have developed protocols for the isolation, expansion and translational application of skeletal stem cell populations with cues from developmental biology, nanotopography and nanoscale architecture as well as biomimetic niche development...

March 2015

  Wed 25 Mar 2015
  15:00 - 17:00
Image: Dr Yanlan MaoSeminar: Dr. Yanlan Mao. Getting in Shape: in vivo and in silico studies of tissue mechanics in growth control
Clark-Kennedy Lecture Theatre, Whitechapel, (not in the QM Innovation Building, but next to it. )
How tissue size and shape are controlled is a fundamental biological question that remains remarkably ill understood. Tissues can grow in a particular direction by controlling the orientation of cell divisions. Using a combination of genetics, live imaging, experimental biophysics and computational modeling, we show that tissue mechanical forces can have an instrumental role in controlling cell shape patterns and cell division orientations. The first part of the presentation will discuss how...
  Wed 18 Mar 2015
  15:00 - 17:00
Image: Prof. Tim HuntSeminar: Prof. Tim Hunt. Getting In and Out of Mitosis
Fogg Lecture Theatre, Fogg Building, Mile End.
  Wed 11 Mar 2015
  15:00 - 17:00
Image: Prof. John GirkinSeminar: Prof. John Girkin. Looking deeply in living biology
Derek Willioughby Lecture Theatre, John Vane Science Centre, Charterhouse Square.
Since its invention around 400 years ago optical microscopy has played a crucial role in biology, as observation is the key component of all science. In many cases the ultimate test is to observe sub-cellular events in vivo and this clearly creates challenges; namely sample movement and the distortion of the images as one observes ever more deeply within the sample. This presentation will explore the recent advances in imaging methods to overcome these issues. Work will be presented in which...

February 2015

  Wed 25 Feb 2015
  15:00 - 17:00
Image: Prof Sara RankinSeminar: Prof. Sara Rankin. Mobilizing progenitor cells from the bone marrow, a pharmacological approach
Derek Willoughby Lecture Theatre, John Vane Science Centre, Charterhouse Square.
Adult bone marrow contains a number of distinct populations of progenitor cells including haematopoietic stem cells, commonly used for bone marrow transplants, and mesenchymal and endothelial progenitor cells that are involved in tissue regeneration. In this talk I will present our data investigating the factors and molecular mechanisms regulating the mobilization of these distinct subsets of progenitor cells from the bone marrow. I will discuss pharmacological strategies to selectively boost...
  Wed 18 Feb 2015
  15:00 - 17:00
Image: Prof Mauro PerrettiSeminar: Prof. Mauro Perretti. Resolution of Inflammation: players and targets (opportunities for bridging disciplines)
Bancroft Building, 1.13 & DS Foyer, Mile End.
Inflammation is an important pathophysiological component of most chronic diseases, carrying an immense global health burden and are a leading cause of mortality (>60% of all deaths) in the world. The cost of providing long-term care for those affected is a growing problem for health services. Although there has been success with anti-inflammatory therapy in chronic diseases, this approach has limitations. In particular, since the inflammatory response is critical for survival, the risk:benefit...
  Wed 11 Feb 2015
  15:00 - 17:00
Image: Prof. Abhay PanditSeminar: Prof. Abhay Pandit. Nature and host inspired biomaterials systems
Clark-Kennedy Lecture Theatre, Whitechapel, (not in the QM Innovation Building, but next to it.)
Biomaterials are no longer considered innate structures and using functionalisation strategies to modulate a desired response whether it is a host or implant is currently an important focus in current research paradigms. Fundamentally, a thorough understanding the host response will enable to design proper functionalisation strategies. Using functionalisation strategies such as enzymatic and hyperbranched linking systems, we have been able to link biomolecules to different structural moieties....
  Wed 4 Feb 2015
  15:00 - 17:00
Image: Dr. Maddy ParsonsSeminar: Dr. Maddy Parsons. Fascin-dependent regulation of cell adhesion
Bancroft Building. 1.13 & DS Foyer, Mile End.
Fascin is an actin-binding and bundling protein that is highly upregulated in most epithelial cancers and strongly correlates with poor patient prognosis. Fascin localizes to filopodia and promotes cell migration in vitro and tumour cell metastasis in vivo. We have previously shown that depletion of fascin results in reduced focal adhesion dynamics through an unknown mechanism. We now demonstrate that fascin is required for microtubule-dependent focal adhesion disassembly and this is controlled...

January 2015

  Wed 28 Jan 2015
  15:00 - 17:00
Image: Manuel TherySeminar: Manuel Thery. Directed cytoskeleton self-organization
David Sizer & DS Foyer in the Bancroft Building, Mile End.
Cytoskeleton architecture supports a large number of cellular functions. Cytoskeleton networks form complex intra-cellular structures resulting from the interplay between intrinsic self-organization properties and the conditions imposed by spatial boundaries. Along these boundaries, cytoskeleton filaments are anchored, repulsed, aligned or reoriented. Such local effects can guide cytoskeleton assembly over relatively large distances and led to the formation of high order structures. The...
  Wed 14 Jan 2015
  15:00 - 17:00
Image: Dr Bart HoogenboomSeminar: Dr Bart Hoogenboom. Selective transport through polymer-coated nanopores: What we can learn from computational simulation and nanomechanical measurements
David Sizer & DS Foyer. Bancroft Building, Mile End.
Nuclear pore complexes (NPCs) are the sole gates for transport between the cell nucleus and the cytoplasm. They contain a transport barrier that consists of unstructured nucleoporins anchored at a ring-structure spanning the nuclear envelope. We have modelled the NPC as a rather generic polymer-coated nanopore [1], to reproduce and test the wide range of proposed scenarios for explaining the transport selectivity through the NPC. Interestingly, variations in interpolymer interaction can cause...

December 2014

  Wed 17 Dec 2014
  15:00 - 16:00
Seminar: Prof. Salmeron-Sanchez. Material-driven protein assembly to engineer the cellular microenvironment.
David Sizer Lecture Theatre , Bancroft Building
Most cells assemble rich protein matrices via an integrin-dependent mechanism that incorporates e.g. fibronectin (FN) molecules into matrix fibrils. The process involves integrin binding and activation of cell contractility to extend FN and expose...
  Wed 3 Dec 2014
  15:00 - 16:00
Seminar: Dr Nick Evans. Mechanics, nanoparticles and growth factors in tissue regeneration.
David Sizer Lecture Theatre , Bancroft Building
During development and wound healing, tissues rapidly change in size, shape, composition, and in their mechanical characteristics. Cells within these tissues are exposed to a variety of forces, including tension, compression and shear, which are...

November 2014

  Wed 5 Nov 2014
  15:00 - 16:00
Prof. Gavin Giovannoni. The medical, social and engineering challenges in developing effective neuroprotective therapies for multiple sclerosis.
David Sizer Lecture Theatre , Bancroft Building

October 2014

  Wed 15 Oct 2014
  15:00 - 16:00
Dr Gwendolen Reilly. Mechanobiology in bone tissue engineering.
David Sizer Lecture Theatre , Bancroft Building
It has been well demonstrated that bone cells respond to mechanical forces in the body and in vitro. These responses can be harnessed to create mechanically stable tissues for regenerative medicine applications. Tissue engineering provides 3D...
  Wed 1 Oct 2014
  15:00 - 16:00
Dr Andrew Dundon. The role/challenges/opportunities for Device Engineering in Drug Delivery at GSK.
David Sizer Lecture Theatre, Bancroft Building.
Andy Dundon, Head of Device Engineering, GSK R&D Ltd will give a talk about the potential opportunities for a career in the development of drug delivery systems within the Pharmaceutical Industry. Andy leads a group who are responsible for the...

September 2014

  Wed 17 Sep 2014
  15:00 - 16:00
Seminar: Prof. Ille Gabeshuber. Tribology, dental sciences, nature and art ? A joyful journey through kindred worlds.
SEMS seminar room
Chitons are animals that paint wonderful images with the magnetic wear particles of their crystalline teeth. Such pieces of art combine beauty and expediency: If the animal had enough to eat, it uses its magnetic sense and navigates home along the...

July 2014

  Wed 2 Jul 2014
  15:00 - 16:00
Seminar: Prof. Fiona Watt. Examining the interactions between keratinocytes and their niche in normal epidermis and in tumours.
PP1 Theatre
The epidermis consists of multiple layers of keratinocytes. Stem cells reside in the basal layer and cells that exit that layer undergo terminal differentiation as they move through the suprabasal layers. Under normal conditions the rate of...

June 2014

  Wed 18 Jun 2014
  15:00 - 16:00
Seminar: Prof. Chris Abel. Microdroplets, compartmentalisation and encapsulation.
PP1 Theatre
The talk will describe our studies using microdroplets as compartments for chemical biology and cell biology, and as a platform for a novel encapsulation technology.
  Thu 5 Jun 2014
  15:00 - 16:00
Seminar: Prof. Dietmar Hutmacher. Tissue engineering of a blood producing organ: Human blood on demand for clinical and experimental applications.
PP1 Theatre
The Hutmacher laboratory recently demonstrated that it is possible to engineer a humanized HSC microenvironment in vivo. The group developed a highly reproducible method to engineer a humanized bone organ, which is able to recapitulate the...
  Wed 4 Jun 2014
  15:00 - 16:00
Seminar: Dr Armando del Rio. How do cells may sense and interpret forces?
PP1 Theatre

May 2014

  Wed 21 May 2014
  15:00 - 16:00
Seminar: Dr. David Farrar. Innovations in bioresorbable polymers for orthopaedic fixation and repair.
PP1 Theatre
Bioresorbable polymers have a wide, and increasing, range of applications within orthopaedic medical devices. These range from suture anchors and screws, through fracture fixation plates to scaffolds for repair of bone and cartilage. These materials...
  Wed 14 May 2014
  15:00 - 16:00
Seminar: Prof. Stephen Mann. Synthetic cellularity via protocell design and construction.
PP1 Theatre
The design and construction of compartmentalized chemical ensembles for modelling complex biological systems, exploring the origin of life, and advancing future living technologies is attracting considerable interest in a wide range of research...
  Thu 8 May 2014
  15:00 - 16:00
Seminar: Prof. Alessandro Gomez. Principles of multiplexed electrosprays and applications to biomaterials synthesis for drug delivery.
PP1 Theatre
The cone-jet electrospray has revolutionized the field of mass spectrometry but, despite the unique ability of this device to produce quasi-monodispersed particles in a phenomenal size range, it has not been applied to other fields. The low flow rate...
  Wed 7 May 2014
  15:00 - 16:00
Seminar: Dr Christoph Ballestrem. Vinculin a mechanotansducing adaptor proteins in control of cell adhesion and migration.
PP1 Theatre
My lab is interested in how cells sense mechanical and biochemical stimuli. Sensing of such stimuli is directed by adhesion receptors (integrins) that transduce the information of the extracellular environment via focal adhesion proteins to the...

April 2014

  Wed 30 Apr 2014
  15:00 - 16:00
Seminar: Prof. Luis-Liz Marzan. Hybrid Nanomaterials for Plasmonic (Bio)Sensing.
PP1 Theatre
Metal nanoparticles display very interesting optical properties, related to localized surface plasmon resonances (LSPR), which give rise to well-defined absorption and scattering peaks in the visible and near-IR spectral range. Such resonances can be...
  Wed 16 Apr 2014
  15:00 - 16:00
Seminar: Dr Pavel Novak. Life at the tip of a nanopipette.
PP1 Theatre
Pipettes, in one form or another, have been used for sampling and transferring liquids in biology and chemistry for almost three centuries. The functionality of this rather simple but effective tool has been dramatically revolutionised in the 80s...
  Wed 2 Apr 2014
  15:00 - 16:00
Seminar: Prof. Martin Knight. The role of Primary cilia in development, health and disease.
PP1 Theatre
Martin Knight's research concerns the area of mechanobiology and how living cells and tissues respond to mechanical forces in terms of their biomechanical properties and regulation of intracellular signalling. This is essential for the health and...

March 2014

  Wed 19 Mar 2014
  15:00 - 16:00
Image: Cleo BishopSeminar: Dr Cleo Bishop. Senescence - from young to old and back again.
PP1 Lecture Theatre
Dr Cleo Bishop With extended culture, normal human mammary epithelial cells (HMECs) eventually reach a state of stable proliferative exhaustion and enter a state of deep senescence, mediated by the cell cycle inhibitor p16INK4a. The acquisition of oncogenic mutation, either in early stage tumourigenesis, or in vitro, enables extended proliferative potential or immortality. Consequently, there is deep interest in determining the role of senescence in vivo in cancer. In addition, advancing age...
  Wed 5 Mar 2014
  15:00 - 16:00
Image: Gerald PollackSeminar: Prof. Gerald Pollack. The Fourth Phase of Water: Beyond Solid, Liquid, and Vapor.
PP1 Lecture Theatre
Prof. Gerald Pollack School children learn that water has three phases: solid, liquid and vapor. But we have recently uncovered a fourth phase. This phase occurs next to water-loving (hydrophilic) surfaces. It is surprisingly extensive, projecting out from the surface by up to millions of molecular layers. And, its properties differ substantially from those of bulk water. Of particular significance is the observation that this fourth phase is charged; and, the water just beyond is...

February 2014

  Wed 26 Feb 2014
  15:00 - 16:00
Image: James KirkpatrickSeminar: Prof. James Kirkpatrick. Scaling up the complexity of culture systems for regeneration.
PP1 Lecture Theatre
Prof. James Kirkpatrick A major question in regenerative medicine is how far in vitro or in vivo models can approach the complexity of the human in vivo situation. This presentation will look critically at both theoretical and practical aspects of this theme and give examples from the author’s own research. Two fields will be examined : bone regeneration, with emphasis on vascularization, and respiratory tract regeneration. We have shown that coculture models can be established, involving...
  Wed 12 Feb 2014
  15:00 - 16:00
Image: Ken SuzukiSeminar: Prof. Ken Suzuki. Stem cell therapy for heart failure: Importance of the cell delivery route.
PP1 Lecture Theatre
Prof. Ken Suzuki Stem cell therapy can induce repair and/or regeneration of the failing myocardium and is a promising new approach for the treatment of heart failure. However, suboptimal cell-delivery route is a major issue. Any current method results in poor retention and survival of donor cells, limiting the therapeutic efficacy of the treatment. This lecture will summarise recent (pre-clinical and clinical) progress of stem cell therapy to the heart. In particular, advantages and...

January 2014

  Wed 29 Jan 2014
  15:00 - 16:00
Image: Peter FratzlSeminar: Prof. Peter Fratzl. Water as a fuel - the materials basis for passive plant movements.
PP1 Lecture Theatre
Prof. Peter Fratzl Dead plant bodies such as seed capsules are able to generate movement by the cyclic absorption of water from the environment. This is based on water swelling of the (secondary) plant cell wall, which is a composite of cellulose nano-fibrils and a matrix containing hemicelluloses and lignin. Cell-wall swelling helps generating growth stresses, e.g., in conifer branches or in the tree stem when subjected to loads. A simple mechanical model for the cell wall predicts that –...
  Wed 22 Jan 2014
  15:00 - 16:00
Image: Pietro CicutaSeminar: Dr Pietro Cicuta. Equilibrium and non-equilibrium dynamics in membranes.
PP1 Lecture Theatre
Dr Pietro Cicuta Work in the last decade has explored the thermodynamics of lipid mixtures, showing for compositions that mimic biological membranes the presence of a critical point for phase separation. This is interesting for two reasons: (a) very nice physics, typical of two dimensional systems; (b) exploring possible biological relevance of this fact. The dynamics of objects embedded in membranes is richer than in the bulk, due to the coupled flows in the membrane and in the adjacent...
  Wed 15 Jan 2014
  15:00 - 16:00
Image: Giuseppe BattagliaSeminar: Prof. Giuseppe Battaglia. How to makes things as simple as possible but not simpler in Biomaterial design
Arts One
Prof. Giuseppe Battaglia Biological systems, including our body, are intrinsically complex and comprise a hierarchy of chemical and physical interaction that join together atoms, molecules, macromolecules and supramolecular structures into functional units far from the thermodynamic equilibrium. Such a complexity is still very much far from our understanding and yet, our self-preservation instinct drives us into interfering with it as much as we can. Whether we need to cure diseases or...

December 2013

  Wed 11 Dec 2013
  15:00 - 16:00
Seminar: Dr Matteo Palma, Biomolecular Nanoarrays: from nanobiotechnology to materials science
Peoples Palace 1 (PP1)
Dr Matteo Palma The School of Biological and Chemical Sciences, Queen Mary University of London SEMS/IoB Seminar Series Coffee/tea/biscuits provided after the seminar The ability to control biomolecules on surfaces with nanometer resolution...
  Wed 4 Dec 2013
  15:00 - 16:00
Image: Dr. Cristina Lo CelsoSeminar: Dr. Cristina Lo Celso, In vivo imaging of quiescent and physiologically activated haematopoietic stem cells
The People's Palace - PP1
Dr. Cristina Lo Celso, Imperial College SEMS/IoB Seminar Series Coffee/tea/biscuits provided after the seminar Abstract: Understanding the mechanisms linking stem cell-niche interaction and stem cell fate is critical for developing regenerative medicine approaches. The nature of such interactions between hematopoietic stem cells (HSC) and the bone marrow (BM) microenvironment has long been elusive due to the difficulty of penetrating bones for direct observation and the fluid nature of...

November 2013

  Wed 27 Nov 2013
  15:00 - 16:00
Image: Seminar: Prof. Molly Stevens, New materials based approaches for regenerative medicine and ultrasensitive biosensing
The People's Palace - PP1
Prof. Molly Stevens, Department of Bioengineering, Imperial College SEMS/IoB Seminar Series Coffee/tea/biscuits provided after the seminar Bio-responsive nanomaterials are of growing importance with potential applications including drug delivery, diagnostics and tissue engineering. A disagreeable side effect of longer life-spans is the failure of one part of the body - the knees, for example - before the body as a whole is ready to surrender. This talk will describe our research on new...
  Wed 20 Nov 2013
  15:00 - 16:00
Image: Dr. Pep PamiesSeminar: Dr. Pep Pamies, Senior Editor of Nature Materials, Appealing to Nature Materials - an editor's view
The People's Palace - PP1
Dr. Pep Pamies, Senior Editor of Nature Materials. Nature Materials offers authors high visibility to their work. A team of full-time, professional editors selects and commissions articles that have the best chances to appeal to the journal's broad audience. In this talk I will convey the editor's perspective on the life of a manuscript after submission to Nature Materials, and provide an overview of recent nanomaterials and biomaterials research published in the journal. SEMS/IoB Seminar...
  Wed 13 Nov 2013
  15:00 - 16:00
Image: Dr. Guillaume CharrasSeminar: Dr. Guillaume Charras, The mechanics of cell monolayers
The People's Palace - PP1
Dr. Guillaume Charras, University College London One-cell thick monolayers are the simplest tissues in multi-cellular organisms, yet they fulfil critical roles in development and normal physiology. In early development, embryonic morphogenesis results largely from monolayer rearrangement and deformation due to internally generated forces. Later, monolayers act as physical barriers separating the internal environment from the exterior and must withstand externally applied forces. Though...
  Wed 6 Nov 2013
  15:00 - 16:00
Image: Prof. Alex SeifalianSeminar: Prof. Alex Seifalian, Development of human organ using nanocomposite scaffold: from lab to patients
The People's Palace - PP1
Prof. Alex Seifalian, Centre for Nanotechnology and Regenerative Medicine, University College London SEMS/IoB Seminar Series Coffee/tea/biscuits provided after the seminar

October 2013

  Wed 30 Oct 2013
  15:00 - 16:00
Image: Prof. William BonfieldSeminar: Prof. William Bonfield, "Biomaterials innovation and technology transfer"
The People's Palace - PP1
"Biomaterials innovation and technology transfer" Prof. William Bonfield, Department of Materials Science and Metallurgy, University of Cambridge "Advances in regenerative medicine are critically dependent on the innovation of second-generation biomaterials which are favourably bioactive ,rather than simply bioinert in a given in vivo situation, through control of the biological processes in adjacent tissues .For skeletal tissues, effective three – dimensional regeneration is enhanced...
  Wed 23 Oct 2013
  15:00 - 16:00
Image: Prof. Rein UlijnSeminar: Prof. Rein Ulijn, Adaptive Nanotechnology through Molecular Networks
The People's Palace - PP1
Prof. Rein Ulijn, Department of Chemistry, University of Strathclyde SEMS/IoB Seminar Series Coffee/tea/biscuits provided after the seminar It is our vision to develop materials and systems that are inspired by the adaptive properties of living systems but are accessible to chemists and may be exploited in technological and biomedical applications. Existing stimuli-responsive nanomaterials and molecules are usually only able to respond to an applied stimulus in a binary (ON/OFF) manner....
  Wed 16 Oct 2013
  15:00 - 16:00
Image: Dr. Chiu Fan LeeSeminar: Dr. Chiu Fan Lee, Phase transitions in cell biology
The People's Palace - PP1
Dr. Chiu Fan Lee, Department of Bioengineering, Imperial College SEMS/IoB Seminar Series Coffee/tea/biscuits provided after the seminar Phase transitions are a ubiquitous physical phenomenon that encompasses, e.g., liquid condensation and water-oil demixing. A phase transition occurs when certain properties of the system changed drastically upon an infinitesimal shift in some of the system parameters. An everyday example is the condensation of vapour into water droplets upon cooling. Such...
  Wed 9 Oct 2013
  15:00 - 16:00
Image: Prof. Fran BalkwillSeminar: Prof. Fran Balkwill, Building a human tumour microenvironment
The People's Palace - PP1
Prof. Fran Balkwill, Barts Cancer Institute, Queen Mary, University of London SEMS/IoB Seminar Series Coffee/tea/biscuits provided after the seminar Even at their earliest stages, human cancers are more than just cells with malignant potential. Cells and extracellular matrix components that normally support and protect the body are coerced into a tumour microenvironment that is central to disease progression. The hypothesis of the CANBUILD project is that recent advances in tissue...
  Wed 2 Oct 2013
  15:00 - 16:00
Image: Dr. Helena AzevedoSeminar: Dr. Helena Azevedo, Peptides and hyaluronan: natural partners for self-assembly and regenerative therapies
The People's Palace - PP1
Dr. Helena Azevedo, School of Engineering & Materials Science, Queen Mary, University of London SEMS/IoB Seminar Series Coffee/tea/biscuits provided after the seminar Sugars and amino acids are the natural building blocks of carbohydrates and proteins, critical constituents of all organisms. Polysaccharides are produced in nature with remarkable chemical and structural diversity. Hyaluronan (HA) is a highly abundant anionic polysaccharide found throughout the mammalian connective tissues....

September 2013

  Wed 25 Sep 2013
  15:00 - 16:00
Image: Dr. Alvaro MataSeminar: Dr. Alvaro Mata, Hierarchical bioengineering: from dynamic self-assembly to 3D patterning
The People's Palace - PP1
Dr Alvaro Mata, SEMS, QMUL SEMS/IoB Seminar Series Coffee/tea/biscuits provided after the seminar Nature generates a widespread variety of materials with well-ordered structure, elaborate geometries, adaptive behaviour, and outstanding properties. What if we had the possibility to design materials with truly hierarchical order from the molecular to the macroscale? What if we could precisely recreate functional 3D environments? What if we had the possibility to create complex materials...
  Wed 18 Sep 2013
  15:00 - 16:00
Image: Prof. Sussan NoursharghSeminar: Prof. Sussan Nourshargh, Leukocyte motility through venular walls in vivo
The People's Palace - PP1
Sussan Nourshargh William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK. SEMS/IoB Seminar Series Coffee/tea/biscuits provided after the seminar Leukocyte motility through venular walls in vivo Migration of leukocytes to sites of injury or inflammation is a crucial component of both innate and adaptive immunity. To penetrate venular walls, leukocytes must migrate through...
  Wed 11 Sep 2013
  15:00 - 16:00
Image: Prof. Xiao Yun XuSeminar: Prof. Xiao Yun Xu, Transport processes in biological systems: from blood flow in the aorta to drug transport in solid tumour
The People's Palace - PP1
Prof. Yun Xu, Department of Chemical Engineering, Imperial College SEMS/IoB Seminar Series Coffee/tea/biscuits provided after the seminar This talk will address two different research topics: (1) our recent work on the analysis of flow in normal and diseased aortas, and (2) a multi-physics model of drug transport in solid tumours. In the first part, examples of patient-specific models of type B aortic dissection will be presented1,2. The second part of the talk will be focused on...

August 2013

  Wed 21 Aug 2013
  11:00 - 12:00
Seminar: Dr Ewa Speiz, Structure-mechanics investigations of mineralized tendon and bone: from micro to macro
SEMS Seminar Room (Third Floor Engineering)
Dr Ewa Speiz is a PDRA at TU Eindhoven, the Netherlands. She is working in the “Function and Soft Mechanics of Biomaterials” group with Dr Cornelis Storm, looking at multiscale mechanics of collagen networks and soft tissues.

July 2013

  Wed 24 Jul 2013
  15:00 - 16:00
Image: Prof. Paul WattonSeminar: Dr. Paul Watton, Modelling the Evolution of Vascular Disease: Aneurysms
SEMS Seminar Room (3rd Floor of the Engineering Building)
Dr. Paul Watton, Department of Computer Science & INSIGNEO Institute of in silico Medicine University of Sheffield, Sheffield, UK In this talk, I will present a general computational framework for modelling vascular disease and illustrate its application to modelling the evolution of abdominal aortic and cerebral aneurysms [1, 2]. Aneurysms appear as dilations of the arterial wall and generally occur in the intracranial arteries and the abdominal aorta. Intracranial aneurysms (IAs) occur on...
  Wed 17 Jul 2013
  15:00 - 16:00
Image: Dr.  John ConnellySeminar: Dr. John Connelly, Biophysical regulation of epidermal cell fate in engineered microenvironments
SEMS Seminar Room (3rd Floor of the Engineering Building)
Dr. John Connelly, Centre for Cutaneous Research, Blizard Institute, Queen Mary, University of London SEMS/IoB Seminar Series Coffee/tea/biscuits provided after the seminar Abstract: The epidermis of the skin provides an essential barrier from the external environment and is continually regenerated throughout adult life. To better understand the role of biophysical cues on keratinocyte cell behaviour, we have developed various engineered model systems, which allow us to precisely...
  Wed 10 Jul 2013
  15:00 - 16:00
Image: Dr. Federico CarpiSeminar: Dr. Federico Carpi - Enabling new biomedical and bioinspired mechatronic systems with electroactive elastomeric actuators
SEMS Seminar Room (3rd Floor of the Engineering Building)
Dr. Federico Carpi, School of Engineering & Materials Science, Queen Mary, University of London The development of a variety of new biomedical and bioinspired mechatronic systems poses challenges that share the need for innovative technologies for electromechanical transduction, so as to enable applications not feasible or even imaginable with conventional approaches. To address this need, new technologies based on electromechanically active polymer (EAP) transducers are progressively...
  Fri 5 Jul 2013
  11:30 - 12:30
Image: James J. FengSeminar: James J. Feng, A particle-based simulation of the mechanics of malaria-infected red blood cells
SEMS Seminar Room
James J. Feng Department of Mathematics and Department of Chemical and Biological Engineering University of British Columbia Vancouver, BC V6T 1Z3, Canada We use computer simulations to investigate the progressive loss of deformability of red blood cells (RBCs) due to malaria infection. The current understanding ascribes the RBC rigidification to a 10-fold increase in membrane stiffness caused by extra cross-linking in the spectrin network. Local measurements by micropipette aspiration,...
  Wed 3 Jul 2013
  15:00 - 16:00
Image: Prof. Vladimir TsukrukSeminar: Prof. Vladimir Tsukruk, Engineered Bionanocomposites
The People's Palace - PP2
Prof. Vladimir Tsukruk, School of Materials Science and Engineering and BIONIC Center, Georgia Institute of Technology, Atlanta, USA I discuss recent results from our research group on designing highly permeable but robust nanoscale multilayered materials for responsive microcapsules, conformal cell protection, and ultrastrong biocomposites. Ultrathin shells from synthetic and natural materials are assembled in order to conduct surface modification and protection of model microparticles,...

June 2013

  Wed 26 Jun 2013
  15:00 - 16:00
Image: Prof. Mark CauldfieldSeminar: Prof. Mark Cauldfield, Device-based therapy for hypertension
The People's Palace - PP2
Prof. Mark Cauldfield, Director of the William Harvey Research Institute, School of Medicine and Dentistry, Queen Mary, University of London SEMS/IoB Seminar Series Coffee/tea/biscuits provided after the seminar There will be 1.5 billion people worldwide with hypertension in 2025. A proportion of those remain uncontrolled and may be resistant to treatment. Device based therapy for proven resistant hypertension is a new procedure with an emerging evidence base of effectiveness and safety. ...
  Wed 19 Jun 2013
  15:00 - 16:00
Image: Dr. Mario OrsiSeminar: Dr. Mario Orsi, Molecular simulation of lipid membranes: from fundamental biophysical properties to the interaction with drugs and antimicrobials
The People's Palace - PP2
Dr. Mario Orsi, School of Engineering & Materials Science, Queen Mary, University of London Lipid membranes are interfacial systems employed by living organisms to enclose cells and organelles, transmit information, control molecular transport, and store energy. Lipids also have many industrial applications, for example in the areas of drug design and targeted delivery, nanotechnology, and biofuel production. This talk will focus on particle-based simulations of membrane systems using the...
  Fri 14 Jun 2013
  11:30 - 12:30
Image: Dr Anne-Virginie Salsac & Prof. Dominique Barthes-Biesel Seminar: Prof. Dominique Barthes-Biesel & Dr Anne-Virginie Salsac, Fluid structure interactions of microcapsules in flow
The People's Palace PP1
Fluid structure interactions of microcapsules in flow Prof. Dominique Barthes-Biesel Dr Anne-Virginie Salsac Bioengineering Department Biomechanics and Biomedical Engineering (UMR CNRS 6600) Université de Technologie de Compiegne B.P. 20529, F60206 Compiegne, FRANCE A capsule is a small liquid droplet enclosed by a thin membrane which has shear elasticity. Capsules are widely found in nature in forms of cells, eggs, seeds, etc. Artificial capsules, which can be fabricated by...

May 2013

  Tue 21 May 2013
  12:30 - 13:30
Image: Dr. Matthew DalbySeminar: Dr. Matthew Dalby, Mesenchymal stem cell response to nano topographical features (and other nanoscale stuff)
SEMS Seminar Room
Mesenchymal stem cell response to nano topographical features (and other nanoscale stuff) Dr. Matthew Dalby, University of Glasgow, Centre for Cell Engineering, Institute of Molecular, Cell and Systems Biology. Abstract: The talk will explore the scale at which cells, including MSCs can respond to nanoscale information. Particularly discussed will be filopodial interaction, MSC targeted osteogenesis and MSC growth with retention of MSC phenotype using nanotopographies. Also discussed...

March 2013

  Mon 25 Mar 2013
  11:00 - 12:30
Seminar: Dr. David Eglin, The AO Foundation: from novel biomaterials to musculoskeletal solutions
SEMS Seminar Room (3rd Floor Engineering)
I would like to kindly invite you to a talk by Dr. David Eglin from the AO Research Institute (ARI) in Davos, Switzerland titled “The AO Foundation: from novel biomaterials to musculoskeletal solutions”on Monday, March 25th, 2013 at 11:00 am in...
  Fri 22 Mar 2013
  15:00 - 16:30
Seminar: Dr. David Hoey, Primary Cilium-Mediated Mechanobiology in Bone
SEMS Seminar room
Abstract: Bone is an exquisitely mechanosensitive organ which constantly adapts its structure to meet the demands of its physical environment. This remodelling phenomenon is ultimately regulated by resident cells, but how these cells sense their...
  Tue 19 Mar 2013
  12:00 - 13:00
Seminar: Prof Eiichi Fukada, Piezoelectricity in Biopolymers and Electrical Stimulation of Bone Growth
SEMS Seminar Room (Third Floor Engineering Building)
  Mon 11 Mar 2013
  12:00 - 13:30
Seminar: Prof. Hua Ai, Magnetic Nanocomposites as MRI Probes: Design and Applications
SEMS Seminar Room
Prof. Hua Ai, Sichun University National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, China Department of Radiology, West China Hospital, Sichuan University, Chengdu, China Magnetic Nanocomposites as MRI Probes:...

January 2013

  Fri 25 Jan 2013
  12:00 - 13:00
Seminar: Prof Geeta K Vemuganti, Research at the Medical School (University of Hyderabad): Opportunities and Challenges
SEMS Seminar Room
"Research at the Medical School (University of Hyderabad): Opportunities and Challenges" Geeta K Vemuganti, Prof & Dean of School of Medical Sciences, University of Hyderabad, AP, India Most countries including India have best of clinicians...

November 2012

  Mon 5 Nov 2012
  13:30 - 16:30
Seminar: 7 Research Seminars, Biomedical Engineering and Materials
SEMS Seminar Room
13.30 Dr Nuria Gavara - University of Goettingen, “Mechanical fingerprints of cells using non-conventional approaches” 13.55 Dr Helena Azevedo - (3B’s Research Group), University of Minho, Portugal, “Complex biomaterial systems emerging...

October 2012

  Thu 4 Oct 2012
  10:15 - 11:00
Seminar: Prof Wenxin Wang, Multifunctional Polymeric Biomaterials for Tissue Engineering and Biodelivery
SEMS Seminar Room
Prof Wenxin Wang, Science Foundation Ireland (SFI) Stokes Lecturer, SFI Principal Investigator Network of Excellence for Functional Biomaterials National Centre for Biomedical Engineering Science Department of Mechanical and Biomedical...
  Thu 4 Oct 2012
  14:45 - 15:30
Seminar: Prof. Manuel Salmerón-Sánchez, Material-driven fibronectin fibrillogenesis
SEMS Seminar Room
Prof. Manuel Salmerón-Sánchez Universitat Politècnica de València, Spain Material-driven fibronectin fibrillogenesis Abstract: Fibronectin (FN) is a cell-adhesive glycoprotein that contains three types of repeating modules (types I, II...
  Tue 2 Oct 2012
  13:00 - 14:00
Seminar: Dr Jing Yang, Discovery of novel polymers surfaces for biomedical application
SEMS Seminar Room
Dr Jing Yang, University of Nottingham

September 2012

  Tue 25 Sep 2012
  12:15 - 13:00
Seminar: Professor Dimitrios Stamatialis, Novel concepts for tissue regeneration
SEMS Seminar Room
Professor Dimitrios Stamatialis, University of Twente Novel concepts for tissue regeneration
  Tue 11 Sep 2012
  10:30 - 12:00
Seminar: Dr Brendan Harley, Patterning biomaterials for regenerative medicine and stem cell engineering
SEMS Seminar Room
Dr Brendan Harley, Dept. of Chemical and Biomolecular Engineering, University of Illinois Patterning biomaterials for regenerative medicine and stem cell engineering ABSTRACT: The extracellular matrix (ECM) is a complex organization of...

March 2012

  Fri 30 Mar 2012
  11:00 - 12:00
Seminar: Dr Mario Orsi 'Molecular dynamics simulations of lipid membranes'
SEMS Seminar Room
Dr Mario Orsi, School of Chemistry, University of Southampton Lipid membranes are interfacial systems employed by living organisms to encapsulate cells and organelles, transmit information, transport molecules, and store energy. Lipid membranes...
  Thu 15 Mar 2012
  15:30 - 16:30
Seminar: Dr Alvaro Mata 'Integrating top-down and bottom-up strategies for the hierarchical control of scaffold biomaterials'
SEMS Seminar Room
Dr Alvaro Mata, Head of the Nanotechnology Platform at Parc Cientific Barcelona, Spain Abstract The scaffold material has become a central and essential component within tissue engineering and regenerative medicine. This leading role has been...
  Thu 8 Mar 2012
  12:00 - 13:30
Seminar: Dr Thomas Franz
SEMS Seminar Room (Third Floor Engineering)
Associate Professor, Head Biomechanical Sciences Cardiovascular Research Unit University of Cape Town

February 2012

  Tue 14 Feb 2012
  09:30 - 10:15
Seminar: Prof. Jake Barralet (McGill university, Montreal, Canada) 'I think therefore Ion'
SEMS Seminar Room
Title: I think therefore Ion Abstract: The field of bioinorganics is well established in the development of a variety of therapies. However, their application to bone regeneration, specifically by way of localized delivery from functional...
  Tue 14 Feb 2012
  10:15 - 11:00
Seminar: Dr. Franck Wiesbrock (Graz University of Technology) "Crosslinked Poly(2-Oxazoline)s and Poly(hydroxyalkanoate)s: Novel Polymeric Scaffolds for Biomedical Applications"
SEMS Seminar Room
Title: "Crosslinked Poly(2-Oxazoline)s and Poly(hydroxyalkanoate)s: Novel Polymeric Scaffolds for Biomedical Applications". Abstract This talk will provide a short overview of my research on poly(2-oxazoline)s and poly(hydroxyalkanoate)s,...
  Mon 13 Feb 2012
  09:30 - 10:15
Seminar: SEMINAR: Dr. Sergio Moya (CIC biomaGUNE, Spain) "From soft matter nanotechnology to nanosafety"
SEMS Seminar Room
Dr. Sergio Moya (CIC biomaGUNE, Spain) Title:"From soft matter nanotechnology to nanosafety".
  Mon 13 Feb 2012
  10:15 - 11:00
Seminar: Dr. Sarah Cartmell (University of Manchester) 'Advances in Orthopaedic Tissue Engineering'
SEMS Seminar Room
Title: 'Advances in Orthopaedic Tissue Engineering' Abstract There is a significant need for novel therapeutic approaches to treat orthopaedic defects such as osteoarthritis and non union fractures. Tissue engineering is an emerging therapy...

January 2012

  Mon 23 Jan 2012
  16:00 - 17:00
Seminar: Dr Stephanie Bryant - Biomimetic Hydrogel Niches: Understanding Biophysical and Biochemical Cues to Promote Integration and Functional Tissue Regeneration
Engineering First Floor, UPC
Dr Stephanie Bryant is an Associate Professor in the Department of Chemical & Biological Engineering, University of Colorado, Boulder, USA. She will be working in SEMS for the next three months, as a Leverhulme Visiting Academic. Her seminar is an...