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Institute of Bioengineering

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Professor Elizabeth Tanner

OBE FRSE FREng PhD(Hon Caus)

Bonfield Professor of Biomedical Materials /
Institute of Bioengineering Director

Department School of Engineering and Materials Science
Email k.e.tanner@qmul.ac.uk
Homepage https://www.sems.qmul.ac.uk/staff/k.e.tanner

IoB Highlights

My research interests are in the development, testing and use of biomaterials for bone and joint replacement. In particular composites of bioactive ceramics and polymers which can encourage bone ongrowth yet have sufficient mechanical properties to be used for load bearing applications. The first of these materials is HAPEXâ?¢ which we manufactured for Gyrus ENT to use in middle ear implants. It is a composite of hydroxyapatite in polyethylene and as can be seen from my publication list we have tried various methods of increasing it mechanical properties. 

The second of these materials are based on poly(lactic acid) and uses drawn fibres to reinforce a poly(lactic acid)-calcium phospate pre-preg. Again we are working on this material to improve its mechanical properties enabling it to be used for fracture fixation and in dental applications. 
Finally I have an interest in the mechanical properties of bone and understanding how it behaves as a material. In this area of my work I am involved in the behaviour of bone under load including the failure mechanisms of cancellous bone the spongy bone at joint ends.

Research Keywords

biomaterials, bone and joint replacement, bioactive ceramics, bioactive polymers

Research Interests

Bonfield Professor of Biomedical Materials, Department of Materials
Adjunct (Visiting) Professor, Department of Orthopaedics, University of Lund, Sweden.

My research interests are in the development, testing and use of biomaterials for bone and joint replacement. In particular composites of bioactive ceramics and polymers which can encourage bone ongrowth yet have sufficient mechanical properties to be used for load bearing applications. The first of these materials is HAPEX? which we manufacture for Gyrus ENT to use in middle ear implants. It is a composite of hydroxyapatite in polyethylene and as can be seen from my publication list we have tried various methods of increasing it mechanical properties.
The second of these materials are based on poly(lactic acid) and uses drawn fibres to reinforce a poly(lactic acid)-calcium phospate pre-preg. Again we are working on this material to improve its mechanical properties enabling it to be used for fracture fixation and in dental applications.
Finally I have an interest in the mechanical properties of bone and understanding how it behaves as a material. In this area of my work I am involved in the behaviour of bone under load including the failure mechanisms of cancellous bone the spongy bone at joint ends.

2005

Mehta JS, Futter CE, Sandeman SR, Faragher RGAF, Hing KA, Tanner KE and Allan BDS (2005). Hydroxyapatite promotes superior keratocyte adhesion and proliferation in comparison with current keratoprosthesis skirt materials. Brit J Ophthalmol  vol. 89, (10) 1356-1362. 10.1136/bjo.2004.064147

2004

Silwood CJL, Chikanza IC, Tanner KE, Shelton JC, Bowsher JG and Grootveld M (2004). Investigation of the molecular nature of low-molecular-mass cobalt(II) ions in isolated osteoarthritic knee-joint synovial fluid. Free Radical Res  vol. 38, (6) 561-571. 10.1080/10715760410001684630

Hing KA, Best SM, Tanner KE, Bonfield W and Revell PA (2004). Mediation of bone ingrowth in porous hydroxyapatite bone graft substitutes. J Biomed Mater Res A  vol. 68, (1) 187-200. 10.1002/jbm.a.10050

HING KA, Tanner KE, Best SM, Bonfield W and Revell PA (2004). Mediation of bone ingrowth in porous hydroxyaptite bone graft substitutes. Journal of Biomedical Materials Research  vol. 68A, 187-200. 10.1002/jbm.a.10050

2000

De Santis R, Anderson P, Tanner KE, Ambrosio L, Nicolais L, Bonfield W and Davis GR (2000). Bone fracture analysis on the short rod chevron-notch specimens using the X-ray computer micro-tomography. Journal of Materials Science: Materials in Medicine  vol. 11, (10) 629-636. 10.1023/A:1008909830421

1999

Hing KA, Best SM, Tanner KE, Bonfield W and Revell PA (1999). Quantification of bone ingrowth within bone-derived porous hydroxyapatite implants of varying density. J Mater Sci Mater Med  vol. 10, (10/11) 663-670. 10.1023/A:1008900127475

1998

Hing KA, Best SM, Tanner KE, Revell PA and Bonfield W (1998). Histomorphological and biomechanical characterization of calcium phosphates in the osseous environment. Proc Inst Mech Eng H  vol. 212, (6) 437-451. 10.1243/0954411981534204

1997

Hing KA, Best SM, Tanner KE, Bonfield W and Revell PA (1997). Biomechanical assessment of bone ingrowth in porous hydroxyapatite. J Mater Sci Mater Med  vol. 8, (12) 731-736. 10.1023/A:1018500309969

1996

Hing KA, Best SM, Revell PA, Tanner KE and Bonfield W (1996). Histomorphometric and biomechanical assessment of bone ingrowth in porous hydroxyapatite. Transactions of The Annual Meeting of The Society For Biomaterials in Conjunction With The International Biomaterials Symposium  vol. 2,

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