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Institute of Bioengineering

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Professor Elizabeth Tanner

OBE FRSE FREng PhD(Hon Caus)

Bonfield Professor of Biomedical Materials /
Institute of Bioengineering Director

Department School of Engineering and Materials Science
Email k.e.tanner@qmul.ac.uk
Homepage https://www.sems.qmul.ac.uk/staff/k.e.tanner

IoB Highlights

My research interests are in the development, testing and use of biomaterials for bone and joint replacement. In particular composites of bioactive ceramics and polymers which can encourage bone ongrowth yet have sufficient mechanical properties to be used for load bearing applications. The first of these materials is HAPEXâ?¢ which we manufactured for Gyrus ENT to use in middle ear implants. It is a composite of hydroxyapatite in polyethylene and as can be seen from my publication list we have tried various methods of increasing it mechanical properties. 

The second of these materials are based on poly(lactic acid) and uses drawn fibres to reinforce a poly(lactic acid)-calcium phospate pre-preg. Again we are working on this material to improve its mechanical properties enabling it to be used for fracture fixation and in dental applications. 
Finally I have an interest in the mechanical properties of bone and understanding how it behaves as a material. In this area of my work I am involved in the behaviour of bone under load including the failure mechanisms of cancellous bone the spongy bone at joint ends.

Research Keywords

biomaterials, bone and joint replacement, bioactive ceramics, bioactive polymers

Research Interests

Bonfield Professor of Biomedical Materials, Department of Materials
Adjunct (Visiting) Professor, Department of Orthopaedics, University of Lund, Sweden.

My research interests are in the development, testing and use of biomaterials for bone and joint replacement. In particular composites of bioactive ceramics and polymers which can encourage bone ongrowth yet have sufficient mechanical properties to be used for load bearing applications. The first of these materials is HAPEX? which we manufacture for Gyrus ENT to use in middle ear implants. It is a composite of hydroxyapatite in polyethylene and as can be seen from my publication list we have tried various methods of increasing it mechanical properties.
The second of these materials are based on poly(lactic acid) and uses drawn fibres to reinforce a poly(lactic acid)-calcium phospate pre-preg. Again we are working on this material to improve its mechanical properties enabling it to be used for fracture fixation and in dental applications.
Finally I have an interest in the mechanical properties of bone and understanding how it behaves as a material. In this area of my work I am involved in the behaviour of bone under load including the failure mechanisms of cancellous bone the spongy bone at joint ends.

2019

Sheafi EM and TANNER KE (2019). Relationship between fatigue parameters and fatigue crack growth in PMMA bone cement. International Journal of Fatigue  vol. 120, 319-328. 10.1016/j.ijfatigue.2018.11.013

Kareem MM, Hodgkinson T, Salmeron Sanchez M, Dalby MJ and TANNER KE (2019). Hybrid Core-Shell Scaffolds for Bone Tissue Engineering. Iop Publishing  Biomedical Materials  vol. 14, 10.1088/1748-605X/aafbf1

2018

Mustafa Z, Ishak NF, Othman R, Ahmad N, Toibah AR, Sheikh Md Fadzullah SH and TANNER KE (2018). In-Vitro Apatite Growth on Porous ?-Tricalcium Phosphate Scaffolds Coated with PHBV. Journal of Advanced Manufacturing Technology  vol. 12, (1(4)) 135-146.

Nair A, Dolan J, Tanner KE, Kerr CM, Jones B, Pollock PJ and Kellett CF (2018). Ultrasound-guided adductor canal block: a cadaver study investigating the effect of a thigh tourniquet. British Journal of Anaesthesia  vol. 121, (4) 890-898. 10.1016/j.bja.2018.04.044

Širka A, Raina DB, Isaksson H, TANNER KE, Smailys A, Kumar A, Tarasevi¿ius Š, Tägil M and Lidgren L (2018). Calcium Sulphate/Hydroxyapatite Carrier for Bone Formation in the Femoral Neck of Osteoporotic Rats. Tissue Engineering Part A  10.1089/ten.tea.2018.0075

2017

Sheafi EM and TANNER KE (2017). S-N Analysis of Fatigue Performance of PMMA Bone Cement: Effects of Testing Specimen Variables and Stress Amplitude. Elsevier  International Journal of Fatigue  vol. 105, 119-127. 10.1016/j.ijfatigue.2017.08.019

Adekanmbi I, Mosher CZ, Lu HH, Riehle M, Kubba H and Tanner KE (2017). Mechanical behaviour of biodegradable AZ31 magnesium alloy after long term in vitro degradation. Mater Sci Eng C Mater Biol Appl  vol. 77, 1135-1144. 10.1016/j.msec.2017.03.216

Coupaud S, Gislason MK, Purcell M, Sasagawa K and Tanner KE (2017). Patient-specific bone mineral density distribution in the tibia of individuals with chronic spinal cord injury, derived from multi-slice peripheral Quantitative Computed Tomography (pQCT) - A cross-sectional study. Bone  vol. 97, 29-37. 10.1016/j.bone.2016.12.014

TANNER KE (2017). Hard Tissue Applications of Biocomposites. Biomedical Composites , Editors: Ambrosio L. Woodhead Publishers 

2016

CATTELL MJ, Theocharopoulos A, Bushby AJ, P¿ng KMY, TANNER KE and wilson RW (2016). Interfacial modulus mapping of layered dental ceramics using nanoindentation., Editors: Kim SH. Journal of Advanced Prosthodontics  vol. 8, (6) 479-488. 10.4047/jap.2016.8.6.479

Ross PD, Guy J, Selfridge J, Kamal B, Bahey N, Tanner KE, Gillingwater TH, Jones RA, Loughrey CM, McCarroll CS, Bailey MES, Bird A and Cobb S (2016). Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes. Human Molecular Genetics  vol. 25, (20) 4389-4404. 10.1093/hmg/ddw269

Tanner KE, Svensson I, Samuelsson F and Flivik G (2016). Finite element study of the acetabulum in cemented hip arthroplasty investigating retention or removal of the subchondral bone plate. Biomed Tech (Berl)  vol. 61, (5) 525-536. 10.1515/bmt-2015-0162

Colquhoun R, Gadegaard N, Healy DM and Tanner KE (2016). Characterisation of CorGlaes(?) Pure 107 fibres for biomedical applications. J Mater Sci Mater Med  vol. 27, (10) 149-149. 10.1007/s10856-016-5752-z

Alfotawi R, Ayoub AF, Tanner KE, Dalby MJ, Naudi KB and McMahon J (2016). A novel surgical approach for the reconstruction of critical-size mandibular defects using calcium sulphate/hydroxyapatite cement, BMP-7 and mesenchymal stem cells-histological assessment. Journal of Biomaterials and Tissue Engineering  vol. 6, (1) 1-11. 10.1166/jbt.2016.1412

2015

Colquhoun R and Tanner KE (2015). Mechanical behaviour of degradable phosphate glass fibres and composites-a review. Biomed Mater  vol. 11, (1) 10.1088/1748-6041/11/1/014105

Sheafi EM and Tanner KE (2015). Influence of test specimen fabrication method and cross-section configuration on tension-tension fatigue life of PMMA bone cement. J Mech Behav Biomed Mater  vol. 51, 380-387. 10.1016/j.jmbbm.2015.07.024

Fitzer SC, Zhu W, Tanner KE, Phoenix VR, Kamenos NA and Cusack M (2015). Ocean acidification alters the material properties of Mytilus edulis shells. J R Soc Interface  vol. 12, (103) 10.1098/rsif.2014.1227

Kamal B, Russell D, Payne A, Constante D, Tanner KE, Isaksson H, Mathavan N and Cobb SR (2015). Biomechanical properties of bone in a mouse model of Rett syndrome. Bone  vol. 71, 106-114. 10.1016/j.bone.2014.10.008

2014

Gislason MK, Coupaud S, Sasagawa K, Tanabe Y, Purcell M, Allan DB and Tanner KE (2014). Prediction of risk of fracture in the tibia due to altered bone mineral density distribution resulting from disuse: a finite element study. Proc Inst Mech Eng H  vol. 228, (2) 165-174. 10.1177/0954411914522438

Al-Fotawei R, Ayoub AF, Heath N, Naudi KB, Tanner KE, Dalby MJ and McMahon J (2014). Radiological assessment of bioengineered bone in a muscle flap for the reconstruction of critical-size mandibular defect. Plos One  vol. 9, (9) 10.1371/journal.pone.0107403

Sheafi EM and Tanner KE (2014). Effects of test sample shape and surface production method on the fatigue behaviour of PMMA bone cement. J Mech Behav Biomed Mater  vol. 29, 91-102. 10.1016/j.jmbbm.2013.08.023

Hessle L, Stordalen GA, Wenglén C, Petzold C, Tanner EK, Brorson S-H, Baekkevold ES, Önnerfjord P, Reinholt FP and Heinegård D (2014). The skeletal phenotype of chondroadherin deficient mice. Plos One  vol. 8, (6) 10.1371/journal.pone.0063080

2013

Wang D, Lucas M and Tanner KE (2013). Characterising the strain and temperature fields in a surrogate bone material subject to power ultrasonic excitation. Strain  vol. 49, (5) 409-419. 10.1111/str.12047

Talal A, McKay IJ, Tanner KE and Hughes FJ (2013). Effects of hydroxyapatite and PDGF concentrations on osteoblast growth in a nanohydroxyapatite-polylactic acid composite for guided tissue regeneration. J Mater Sci Mater Med  vol. 24, (9) 2211-2221. 10.1007/s10856-013-4963-9

Hessle L, Stordalen GA, Wenglén C, Petzold C, Tanner EK, Brorson SH, Baekkevold ES, Önnerfjord P, Reinholt FP and Heinegård D (2013). Erratum: The skeletal phenotype of chondroadherin deficient mice (PLoS ONE (2013) 8:7 DOI: 10.1371/annotation/cb7d7b4c-624f-46e6-957e-13b355ca8e02). Plos One  vol. 8, (7) 10.1371/annotation/cb7d7b4c-624f-46e6-957e-13b355ca8e02

Vasiev I, Greer AIM, Khokhar AZ, Stormonth-Darling J, Tanner KE and Gadegaard N (2013). Self-folding nano- and micropatterned hydrogel tissue engineering scaffolds by single step photolithographic process. Microelectronic Engineering  vol. 108, 76-81. 10.1016/j.mee.2013.04.003

Alfotawi R, Naudi K, Dalby MJ, Tanner KE, Mcmahon JD and Ayoub A (2013). Assessment of cellular viability on calcium sulphate/hydroxyapatite injectable scaffolds. Journal of Tissue Engineering  vol. 4, (1) 1-12. 10.1177/2041731413509645

2012

Mellon SJ and Tanner KE (2012). Bone and its adaptation to mechanical loading: A review. International Materials Reviews  vol. 57, (5) 235-255. 10.1179/1743280412Y.0000000008

Tanner KE (2012). Materials science. Small but extremely tough. Science  vol. 336, (6086) 1237-1238. 10.1126/science.1222642

Noailly J, Ambrosio L, Elizabeth Tanner K, Planell JA and Lacroix D (2012). In silico evaluation of a new composite disc substitute with a L3-L5 lumbar spine finite element model. Eur Spine J  vol. 21 Suppl 5, S675-S687. 10.1007/s00586-011-1716-7

Raucci MG, Gloria A, De Santis R, Ambrosio L and Tanner E (2012). Introduction to biomaterials for spinal surgery. 10.1016/B978-1-84569-986-4.50001-5

Tanner E (2012). Optimising the properties of injectable materials for vertebroplasty and kyphoplasty. Biomaterials For Spinal Surgery  10.1016/B978-1-84569-986-4.50011-8

Gloria A, De Santis R, Ambrosio L and Tanner E (2012). Artificial intervertebral discs. Biomaterials For Spinal Surgery  10.1016/B978-1-84569-986-4.50008-8

Savalani MM, Hao L, Dickens PM, Zhang Y, Tanner KE and Harris RA (2012). The effects and interactions of fabrication parameters on the properties of selective laser sintered hydroxyapatite polyamide composite biomaterials. Rapid Prototyping Journal  vol. 18, (1) 16-27. 10.1108/13552541211193467

Ambrosio L and Tanner E (2012). Biomaterials for Spinal Surgery. 10.1533/9780857096197

Brydone AS, Morrison DSS, Stormonth-Darling J, Meek RDM, Tanner KE and Gadegaard N (2012). Design and fabrication of a 3D nanopatterned PEEK implant for cortical bone regeneration in a rabbit model. European Cells and Materials  vol. 24, (SUPPL. 1)

2011

Wang J-S, Garellick G, Kjellson F, Tanner E and Flivik G (2011). Modified femoral pressuriser generates a longer lasting high pressure during cement pressurisation. J Orthop Surg Res  vol. 6, 10.1186/1749-799X-6-54

Huesa C, Yadav MC, Finnilä MAJ, Goodyear SR, Robins SP, Tanner KE, Aspden RM, Millán JL and Farquharson C (2011). PHOSPHO1 is essential for mechanically competent mineralization and the avoidance of spontaneous fractures. Bone  vol. 48, (5) 1066-1074. 10.1016/j.bone.2011.01.010

Gloria A, De Santis R, Ambrosio L, Causa F and Tanner KE (2011). A multi-component fiber-reinforced PHEMA-based hydrogel/HAPEX? device for customized intervertebral disc prosthesis. J Biomater Appl  vol. 25, (8) 795-810. 10.1177/0885328209360933

2010

Tanner KE (2010). Bioactive composites for bone tissue engineering. Proc Inst Mech Eng H  vol. 224, (12) 1359-1372. 10.1243/09544119JEIM823

Tanner KE and Dalby MJ (2010). Special issue on bone tissue engineering. Proc Inst Mech Eng H  vol. 224, (12) i-iv. 10.1177/095441191022401201

Tanner KE (2010). Bioactive ceramic-reinforced composites for bone augmentation. J R Soc Interface  vol. 7 Suppl 5, S541-S557. 10.1098/rsif.2010.0229.focus

Tanner KE, Wang J-S, Kjellson F and Lidgren L (2010). Comparison of two methods of fatigue testing bone cement. Acta Biomater  vol. 6, (3) 943-952. 10.1016/j.actbio.2009.09.009

2009

Zhang Y, Hao L, Savalani MM, Harris RA, Di Silvio L and Tanner KE (2009). In vitro biocompatibility of hydroxyapatite-reinforced polymeric composites manufactured by selective laser sintering. J Biomed Mater Res A  vol. 91, (4) 1018-1027. 10.1002/jbm.a.32298

Tanner KE (2009). Composites based on degradable polymers. Degradable Polymers For Skeletal Implants 

Talal A, Waheed N, Al-Masri M, McKay IJ, Tanner KE and Hughes FJ (2009). Absorption and release of protein from hydroxyapatite-polylactic acid (HA-PLA) membranes. J Dent  vol. 37, (11) 820-826. 10.1016/j.jdent.2009.06.014

Tanner KE (2009). Hard tissue applications of biocomposites. Biomedical Composites  10.1533/9781845697372.1.44

Hao L, Savalani MM, Harris RA, Zhang Y and Tanner KE (2009). Rapid manufacturing of bioceramic/polymer composite implants by selective laser sintering. International Journal of Computer Applications in Technology  vol. 36, (1) 25-31. 10.1504/IJCAT.2009.026667

Talal A, Tanner KE, Billington R and Pearson GJ (2009). Effect of ultrasound on the setting characteristics of glass ionomer cements studied by Fourier transform infrared spectroscopy. J Mater Sci Mater Med  vol. 20, (1) 405-411. 10.1007/s10856-008-3578-z

2008

Pino M, Stingelin N and Tanner KE (2008). Nucleation and growth of apatite on NaOH-treated PEEK, HDPE and UHMWPE for artificial cornea materials. Acta Biomater  vol. 4, (6) 1827-1836. 10.1016/j.actbio.2008.05.004

Khan AS, Phillips MJ, Tanner KE and Wong FS (2008). Comparison of the visco-elastic behavior of a pre-impregnated reinforced glass fiber composite with resin-based composite. Dent Mater  vol. 24, (11) 1534-1538. 10.1016/j.dental.2008.03.017

Zhang Y, Hao L, Savalani MM, Harris RA and Tanner KE (2008). Characterization and dynamic mechanical analysis of selective laser sintered hydroxyapatite-filled polymeric composites. J Biomed Mater Res A  vol. 86, (3) 607-616. 10.1002/jbm.a.31622

Zhang Y and Tanner KE (2008). Effect of filler surface morphology on the impact behaviour of hydroxyapatite reinforced high density polyethylene composites. J Mater Sci-Mater M  vol. 19, (2) 761-766. 10.1007/s10856-007-3119-1

2007

Savalani MM, Hao L, Zhang Y, Tanner KE and Harris RA (2007). Fabrication of porous bioactive structures using the selective laser sintering technique. P I Mech Eng H  vol. 221, (H8) 873-886. 10.1243/09544119JEIM232

Hao L, Savalani MM, Zhang Y, Tanner KE, Heath RJ and Harris RA (2007). Characterization of selective laser-sintered hydroxyapatite-based biocomposite structures for bone replacement. P R Soc A  vol. 463, (2084) 1857-1869. 10.1098/rspa.2007.1854

Kjellson F, Abdulghani S, Tanner KE, McCarthy ID and Lidgren L (2007). Effect of iodixanol particle size on the mechanical properties of a PMMA based bone cement. J Mater Sci-Mater M  vol. 18, (6) 1043-1051. 10.1007/s10856-006-0116-8

Zhang Y, Tanner KE, Gurav N and Di Silvio L (2007). In vitro osteoblastic response to 30 vol% hydroxyapatite-polyethylene composite. J Biomed Mater Res A  vol. 81A, (2) 409-417. 10.1002/jbm.a.31078

Cortes DA, Hogg PJ, Tanner KE and Ren G (2007). Mechanical properties of carbon-fibre reinforced silicate matrix composites. Mater Design  vol. 28, (5) 1547-1554. 10.1016/j.matdes.2006.02.014

2006

Zou H, Mellon S, Syms RRA and Tanner KE (2006). 2-Dimensional MEMS dielectrophoresis device for osteoblast cell stimulation. Biomed Microdevices  vol. 8, (4) 353-359. 10.1007/s10544-006-9818-4

Osei NA, Bradley BM, Culpan P, Mitchell JB, Barry M and Tanner KE (2006). Relationship between locking-bolt torque and load pre-tension in the llizarov frame. Injury  vol. 37, (10) 941-945. 10.1016/j.injury.2006.02.019

Hao L, Savalani MM, Zhang Y, Tanner KE and Harris RA (2006). Effects of material morphology and processing conditions on the characteristics of hydroxyapatite and high-density polyethylene biocomposites by selective laser sintering. P I Mech Eng L-J Mat  vol. 220, (L3) 125-137. 10.1243/14644207JMDA92

Hao L, Savalani MM, Zhang Y, Tanner KE and Harris RA (2006). Selective laser sintering of hydroxyapatite reinforced polyethylene composites for bioactive implants and tissue scaffold development. P I Mech Eng H  vol. 220, (H4) 521-531. 10.1243/09544119JEIM67

Sanginario V, Ginebra MP, Tanner KE, Planell JA and Ambrosio L (2006). Biodegradable and semi-biodegradable composite hydrogels as bone substitutes: morphology and mechanical characterization. J Mater Sci-Mater M  vol. 17, (5) 447-454. 10.1007/s10856-006-8472-y

Joseph R, Martyn MT, Tanner KE and Coates PD (2006). Interfacial stick-slip transition in hydroxyapatite filled high density polyethylene composite. B Mater Sci  vol. 29, (1) 85-89. 10.1007/bf02709361

2005

Barker DS, Tanner KE and Ryd L (2005). A circumferentially flanged tibial tray minimizes bone-tray shear micromotion. P I Mech Eng H  vol. 219, (H6) 449-456. 10.1243/095441105X34464

Mehta JS, Futter CE, Sandeman SR, Faragher RGAF, Hing KA, Tanner KE and Allan BDS (2005). Hydroxyapatite promotes superior keratocyte adhesion and proliferation in comparison with current keratoprosthesis skirt materials. Br J Ophthalmol  vol. 89, (10) 1356-1362. 10.1136/bjo.2004.064147

Wang JS, Diaz J, Sabokbar A, Athanasou N, Kjellson F, Tanner KE, McCarthy ID and Lidgren L (2005). In vitro and in vivo biological responses to a novel radiopacifying agent for bone cement. J Roy Soc Interface  vol. 2, (2) 71-78. 10.1098/rsif.2004.0009

Joseph R and Tanner KE (2005). Effect of morphological features and surface area of hydroxyapatite on the fatigue behavior of hydroxyapatite-polyethylene composites. Biomacromolecules  vol. 6, (2) 1021-1026. 10.1021/bm0493180

2004

Eniwumide JO, Joseph R and Tanner KE (2004). Effect of particle morphology and polyethylene molecular weight on the fracture toughness of hydroxyapatite reinforced polyethylene composite. J Mater Sci Mater Med  vol. 15, (10) 1147-1152. 10.1023/B:JMSM.0000046398.17027.97

Kjellson F, Almén T, Tanner KE, McCarthy ID and Lidgren L (2004). Bone cement X-ray contrast media: A clinically relevant method of measuring their efficacy. Journal of Biomedical Materials Research - Part B Applied Biomaterials  vol. 70, (2) 354-361.

Silwood CJL, Chikanza IC, Tanner KE, Shelton JC, Bowsher JG and Grootveld M (2004). Investigation of the molecular nature of low-molecular-mass cobalt(II) ions in isolated osteoarthritic knee-joint synovial fluid. Free Radic Res  vol. 38, (6) 561-571. 10.1080/10715760410001684630

Nilsson M, Wang JS, Wielanek L, Tanner KE and Lidgren L (2004). Biodegradation and biocompatability of a calcium sulphate-hydroxyapatite bone substitute. J Bone Joint Surg Br  vol. 86, (1) 120-125. 10.1302/0301-620X.86B1.14040

HING KA, Tanner KE, Best SM, Bonfield W and Revell PA (2004). Mediation of bone ingrowth in porous hydroxyaptite bone graft substitutes. Journal of Biomedical Materials Research  vol. 68A, 187-200. 10.1002/jbm.a.10050

TANNER KE, Wang J-S, Lidgren L, McCarthy ID, Kjellson F, Diaz J and Sabokbar A (2004). In Vitro and In Vivo Biological Responses to a Vovel Radiopacifing Agent for Bone Cement. Journal of The Royal Society: Interface 

TANNER KE, Lidgren L, Wielanek L, Wang J-S and Nilsson M (2004). Biodegradation and Biocompatibility of a Calcium Sulphate-Hydroxyapatite Bone Substitute. Journal of Bone and Joint Surgery  vol. 86-B, (1) 120-125.

TANNER KE, Lidgren L, Almen T, Kjellson F and McCarthy ID (2004). Bone Cement X-ray Contrast Media: A Clinically Relevant Method of Measuring their Efficacy. Journal of Biomedical Materials Research  vol. 70B, (2) 354-371. 10.1002/jbm.b.30060

Hing KA, Best SM, Tanner KE, Bonfield W and Revell PA (2004). Mediation of bone ingrowth in porous hydroxyapatite bone graft substitutes. J Biomed Mater Res A  vol. 68, (1) 187-200. 10.1002/jbm.a.10050

2003

Zhang Y and Tanner KE (2003). Impact behavior of hydroxyapatite reinforced polyethylene composites. J Mater Sci-Mater M  vol. 14, (1) 63-68. 10.1023/A:1021553504549

TANNER KE, Wielanek L, Lidgren L, Nilsson M and Wang JS (2003). Factors Influencing the Compressive Strength of an Injectable Calcium Sulfate-Hydroxyapatite Cement. Journal of Materials Science: Materials in Medicine  vol. 14, (5) 399-404. 10.1023/A:1023254632704

Vashishth D, Tanner KE and Bonfield W (2003). Experimental validation of a microcracking-based toughening mechanism for cortical bone. J Biomech  vol. 36, (1) 121-124. 10.1016/S0021-9290(02)00319-6

2002

Olsson O, Tanner KE, Ceder L and Ryd L (2002). A biomechanical study on fixation stability with twin hook or lag screw in artificial cancellous bone. Int Orthop  vol. 26, (6) 349-355. 10.1007/s00264-002-0385-x

Joseph R, McGregor WJ, Martyn MT, Tanner KE and Coates PD (2002). Effect of hydroxyapatite morphology/surface area on the rheology and processability of hydroxyapatite filled polyethylene composites. Biomaterials  vol. 23, (21) 4295-4302. 10.1016/s0142-9612(02)00192-8

Yuan X, Ryd L, Tanner KE and Lidgren L (2002). Roentgen single-plane photogrammetric analysis (RSPA.) A new approach to the study of musculoskeletal movement. J Bone Joint Surg Br  vol. 84, (6) 908-914. 10.1302/0301-620X.84B6.11146

Rich J, Tuominen J, Kylma J, Seppala J, Nazhat SN and Tanner KE (2002). Lactic acid based PEU/HA and PEU/BCP composites: Dynamic mechanical characterization of hydrolysis. J Biomed Mater Res  vol. 63, (3) 346-353. 10.1002/jbm.10232

Bleach NC, Nazhat SN, Tanner KE, Kellomaki M and Tormala P (2002). Effect of filler content on mechanical and dynamic mechanical properties of particulate biphasic calcium phosphate-polylactide composites. Biomaterials  vol. 23, (7) 1579-1585. 10.1016/s0142-9612(01)00283-6

Joseph R, McGregor WJ, Martyn MT, Tanner KE, Coates PD and Bonfield W (2002). Effect of polymer matrix on the rheology of hydroxyapatite-filled polyethylene composites. Polym Eng Sci  vol. 42, (2) 326-335. 10.1002/pen.10951

Bonner M, Saunders LS, Ward IM, Davies GW, Wang M, Tanner KE and Bonfield W (2002). Anisotropic mechanical properties of oriented HAPEX (TM). J Mater Sci  vol. 37, (2) 325-334. 10.1023/A:1013652312670

TANNER KE, Znaor N, Goodship AE, Gaughan EM, DeBowes RM and Murray RC (2002). The Effect of Intra-articular Methylprednisolone Acetate and Exercise on Equine Carpal Subchondral and Cancellous Bone Microhardness. Equine Veterinary Journal  vol. 34, (3) 306-310. 10.2746/042516402776185994

TANNER KE, Lidgren L, Yuan X and Ryd L (2002). Rontgen Single-Plane Stereophotogrammetric Analysis (RSPA). A New Approach for the STudy of Musculo-Skeletal Movement. Journal of Bone and Joint Surgery  vol. 84-B, (6) 908-914.

TANNER KE, Ryd L, Lauge-Pederson H and Aspenberg P (2002). Dome-shaped versus Flat Arthrodesis of the Ankle Joint: Strength Measurements using Synthetic Cancellous Bone. Proceedings of The Institution of Mechanical Engineers: Part H, Engineering in Medicine  vol. 216-H, (1) 43-49.

Lauge-Pedersen H, Aspenberg P, Ryd L and Tanner KE (2002). Arch-shaped versus flat arthrodesis of the ankle joint: strength measurements using synthetic cancellous bone. P I Mech Eng H  vol. 216, (H1) 43-49. 10.1243/0954411021536270

Thompson MS, Northmore-Ball MD and Tanner KE (2002). Effects of acetabular resurfacing component material and fixation on the strain distribution in the pelvis. P I Mech Eng H  vol. 216, (H4) 237-245. 10.1243/09544110260138727

Cortes DA, Hogg PJ, Tanner KE and Escobedo JC (2002). Mechanical properties of a novel bioactive ceramic system. Arch Metall  vol. 47, (4) 409-419.

Hogg PJ, TANNER KE, Cortes DA and Escobedo JC (2002). Mechanical Properties of a Novel Bioactive Ceramic Systemtem. Archives of Metallurgy  vol. 47, (4) 409-419.

2001

Vashishth D, Tanner KE and Bonfield W (2001). Fatigue of cortical bone under combined axial-torsional loading. J Orthopaed Res  vol. 19, (3) 414-420. 10.1016/S0736-0266(00)00036-X

Tanner KE (2001). A quarter century of European Biomaterials Conferences. J Mater Sci-Mater M  vol. 12, (10-12) 847-848. 10.1023/A:1012825817780

Bonner M, Ward IM, McGregor W, Tanner KE and Bonfield W (2001). Hydroxyapatite/polypropylene composite: A novel bone substitute material. J Mater Sci Lett  vol. 20, (22) 2049-2051. 10.1023/A:1013594125371

Nazhat SN, Kellomäki M, Törmälä P, Tanner KE and Bonfield W (2001). Dynamic mechanical characterization of biodegradable composites of hydroxyapatite and polylactides. J Biomed Mater Res  vol. 58, (4) 335-343. 10.1002/jbm.1026

TANNER KE, Kjellson F, Lidgren L, Klaveness J, Almen T, Wang J-S and Mattson A (2001). Tensile Mechanical Properties of a Bone Cement containing Non-Ionic Contrast Media. Journal of Materials Science: Materials in Medicine  vol. 12, (10-12) 889-894.

Joseph R, Martyn MT, Tanner KE, Coates PD and Bonfield W (2001). Rheological characterisation of hydroxyapatite filled polyethylene composites Part 2 - Isothermal compressibility and wall slip. Plast Rubber Compos  vol. 30, (5) 205-212. 10.1179/146580101101541633

TANNER KE, Thompson MS and Northmore-Ball MD (2001). Tensile mechanical Properties of Polyacetal after 1 and 6 months immersion in Ringer's solution. Journal of Materials Science: Materials in Medicine  vol. 12, (10-12) 883-888.

Joseph R, Martyn MT, Tanner KE, Coates PD and Bonfield W (2001). Rheological characterisation of hydroxyapatite filled polyethylene composites Part 1 - Shear and extensional behaviour. Plast Rubber Compos  vol. 30, (5) 197-204. 10.1179/146580101101541624

TANNER KE (2001). Editorial: A QuaterCentury of European Biomaterials Conference. Journal of Materials Science: Matrials in Medicine  vol. 12, (10-12) 847-848.

Bleach NC, Tanner KE, Kellomaki M and Tormala P (2001). Effect of filler type on the mechanical properties of self-reinforced polylactide-calcium phosphate composites. Journal of Materials Science-Materials in Medicine  vol. 12, (10-12) 911-915. 10.1023/A:1012884310027

2000

Thompson MS, Dawson T, Kuiper JH, Northmore-Ball MD and Tanner KE (2000). Acetabular morphology and resurfacing design. J Biomech  vol. 33, (12) 1645-1653. 10.1016/s0021-9290(00)00115-9

Nazhat SN, Joseph R, Wang M, Smith R, Tanner KE and Bonfield W (2000). Dynamic mechanical characterization of hydroxyapatite reinforced polyethylene: effect of particle size. J Mater Sci Mater Med  vol. 11, (10) 621-628. 10.1023/A:1008957729512

De Santis R, Anderson P, Tanner KE, Ambrosio L, Nicolais L, Bonfield W and Davis GR (2000). Bone fracture analysis on the short rod chevron-notch specimens using the X-ray computer micro-tomography. J Mater Sci Mater Med  vol. 11, (10) 629-636. 10.1023/A:1008909830421

McGregor WJ, Tanner KE, Bonfield W, Bonner MJ, Saunders LS and Ward IM (2000). Fatigue properties of isotropic and hydrostatically extruded HAPEXTM. Journal of Materials Science Letters  vol. 19, (20) 1787-1788. 10.1023/A:1006721802102

That PT, Tanner KE and Bonfield W (2000). Fatigue characterization of a hydroxyapatite-reinforced polyethylene composite. I. Uniaxial fatigue. J Biomed Mater Res  vol. 51, (3) 453-460. 10.1002/1097-4636(20000905)51:3<453::AID-JBM20>3.0.CO;2-Q

Ton That PT, Tanner KE and Bonfield W (2000). Fatigue characterization of a hydroxyapatite-reinforced polyethylene composite. II. Biaxial fatigue. J Biomed Mater Res  vol. 51, (3) 461-468. 10.1002/1097-4636(20000905)51:3<461::AID-JBM21>3.0.CO;2-M

Vashishth D, Tanner KE and Bonfield W (2000). Contribution, development and morphology of microcracking in cortical bone during crack propagation. J Biomech  vol. 33, (9) 1169-1174. 10.1016/s0021-9290(00)00010-5

Wang M, Ladizesky NH, Tanner KE, Ward IM and Bonfield W (2000). Hydrostatically extruded HAPEXTM. Journal of Materials Science  vol. 35, (4) 1023-1030. 10.1023/A:1004731315328

1999

New AM, Northmore-Ball MD, Tanner KE and Cheah SK (1999). In vivo measurement of acetabular cement pressurization using a simple new design of cement pressurizer. J Arthroplasty  vol. 14, (7) 854-859. 10.1016/S0883-5403(99)90037-2

Hing KA, Best SM, Tanner KE, Bonfield W and Revell PA (1999). Quantification of bone ingrowth within bone-derived porous hydroxyapatite implants of varying density. J Mater Sci Mater Med  vol. 10, (10/11) 663-670. 10.1023/A:1008900127475

Sala M, Taylor M and Tanner KE (1999). Torsional stability of primary total knee replacement tibial prostheses: a biomechanical study in cadaveric bone. J Arthroplasty  vol. 14, (5) 610-615. 10.1016/S0883-5403(99)90085-2

1998

Borzacchiello A, Ambrosio L, Nicolais L, Harper EJ, Tanner KE and Bonfield W (1998). Comparison between the polymerization behavior of a new bone cement and a commercial one: modeling and in vitro analysis. J Mater Sci Mater Med  vol. 9, (12) 835-838. 10.1023/A:1008996112042

Borzacchiello A, Ambrosio L, Nicolais L, Harper EJ, Tanner KE and Bonfield W (1998). Isothermal and non-isothermal polymerization of a new bone cement. J Mater Sci Mater Med  vol. 9, (6) 317-324. 10.1023/A:1008898712929

Bonfield W, Wang M and Tanner KE (1998). Interfaces in analogue biomaterials. Acta Materialia  vol. 46, (7) 2509-2518. 10.1016/S1359-6454(98)80035-9

Taylor M, Tanner KE and Freeman MA (1998). Finite element analysis of the implanted proximal tibia: a relationship between the initial cancellous bone stresses and implant migration. J Biomech  vol. 31, (4) 303-310. 10.1016/s0021-9290(98)00022-0

Suwanprateeb J, Tanner KE, Turner S and Bonfield W (1998). Influence of sterilization by gamma irradiation and of thermal annealing on creep of hydroxyapatite-reinforced polyethylene composites. J Biomed Mater Res  vol. 39, (1) 16-22. 10.1002/(SICI)1097-4636(199801)39:1<16::AID-JBM3>3.0.CO;2-L

Tanner E and Planell J (1998). Special issue on biomaterials: Part 1. Proceedings of The Institution of Mechanical Engineers Part H-Journal of Engineering in Medicine  vol. 212, (H2) I-II.

Tanner KE and Planell JA (1998). Special issue on biomaterials: Part 2. Proceedings of The Institution of Mechanical Engineers Part H-Journal of Engineering in Medicine  vol. 212, (H6) I-II.

Hing KA, Best SM, Tanner KE, Revell PA and Bonfield W (1998). Histomorphological and biomechanical characterization of calcium phosphates in the osseous environment. Proc Inst Mech Eng H  vol. 212, (6) 437-451. 10.1243/0954411981534204

1997

Hing KA, Best SM, Tanner KE, Bonfield W and Revell PA (1997). Biomechanical assessment of bone ingrowth in porous hydroxyapatite. J Mater Sci Mater Med  vol. 8, (12) 731-736. 10.1023/A:1018500309969

Suwanprateeb J, Tanner KE, Turner S and Bonfield W (1997). Influence of Ringer's solution on creep resistance of hydroxyapatite reinforced polyethylene composites. J Mater Sci Mater Med  vol. 8, (8) 469-472. 10.1023/A:1018522025474

Taylor M and Tanner KE (1997). Fatigue failure of cancellous bone: a possible cause of implant migration and loosening. J Bone Joint Surg Br  vol. 79, (2) 181-182. 10.1302/0301-620X.79B2.7461

Bonfield W and Tanner KE (1997). Biomaterials - A new generation. Materials World  vol. 5, (1) 18-20.

Taylor ME, Tanner KE, Freeman MAR and Yettram AL (1997). Stress and strain distribution within the intact femur: Compression or bending? Response. Medical Engineering & Physics  vol. 19, (1) 99-100. 10.1016/S1350-4533(96)00044-6

1996

Hing KA, Best SM, Revell PA, Tanner KE and Bonfield W (1996). Histomorphometric and biomechanical assessment of bone ingrowth in porous hydroxyapatite. Transactions of The Annual Meeting of The Society For Biomaterials in Conjunction With The International Biomaterials Symposium  vol. 2,

Taylor ME, Tanner KE, Freeman MA and Yettram AL (1996). Stress and strain distribution within the intact femur: compression or bending? Med Eng Phys  vol. 18, (2) 122-131. 10.1016/1350-4533(95)00031-3

Deb S, Wang M, Tanner KE and Bonfield W (1996). Hydroxyapatite-polyethylene composites: Effect of grafting and surface treatment of hydroxyapatite. Journal of Materials Science: Materials in Medicine  vol. 7, (4) 191-193. 10.1007/BF00119729

1995

Suwanprateeb , Tanner KE, Turner S and Bonfield W (1995). Creep in polyethylene and hydroxyapatite reinforced polyethylene composites. 10.1007/BF00134321

Taylor M, Tanner KE, Freeman MA and Yettram AL (1995). Cancellous bone stresses surrounding the femoral component of a hip prosthesis: an elastic-plastic finite element analysis. Med Eng Phys  vol. 17, (7) 544-550. 10.1016/1350-4533(95)00018-I

Tanner KE, Yettram AL, Loeffler M, Goodier WD, Freeman MA and Bonfield W (1995). Is stem length important in uncemented endoprostheses? Med Eng Phys  vol. 17, (4) 291-296. 10.1016/1350-4533(95)90854-5

Tanner K, Yettram AL, Loeffler M, Goodier WD, Freeman MAR and Bonfield W (1995). Erratum: Is stem length important in uncemented endoprostheses? (Med. Eng. Phys. 1995; 17: (291-296)). Medical Engineering and Physics  vol. 17, (6) 10.1016/1350-4533(95)94331-V

1992

Bhatia D, Tanner KE, Bonfield W and Citron ND (1992). Factors affecting the strength of flexor tendon repair. J Hand Surg Br  vol. 17, (5) 550-552. 10.1016/s0266-7681(05)80240-2

Bhatia D, Tanner KE, Bonfield W and Citron ND (1992). Factors Affecting the Strength of Flexor Tendon Repair. Journal of Hand Surgery (British and European Volume)  vol. 17, (5) 550-552. 10.1016/S0266-7681(05)80240-2

1991

Doyle C, Tanner ET and Bonfield W (1991). In vitro and in vivo evaluation of polyhydroxybutyrate and of polyhydroxybutyrate reinforced with hydroxyapatite. Biomaterials  vol. 12, (9) 841-847. 10.1016/0142-9612(91)90072-i

Deligianni DD, Missirlis YF, Tanner KE and Bonfield W (1991). Mechanical behaviour of trabecular bone of the human femoral head in females. Journal of Materials Science: Materials in Medicine  vol. 2, (3) 168-175. 10.1007/BF00692976

Tanner KE, Warren NP and Coombs RR (1991). Ochronosis of the hip joint. Case report with biomechanical study. Scand J Rheumatol  vol. 20, (1) 63-64. 10.3109/03009749109165924

1990

Sharp DJ, Tanner KE and Bonfield W (1990). Measurement of the density of trabecular bone. J Biomech  vol. 23, (8) 853-857. 10.1016/0021-9290(90)90032-x

1989

Nunn D, Freeman MA, Tanner KE and Bonfield W (1989). Torsional stability of the femoral component of hip arthroplasty. Response to an anteriorly applied load. J Bone Joint Surg Br  vol. 71, (3) 452-455.

1988

Tanner KE, Bonfield W, Nunn D and Freeman MA (1988). Rotational movement of femoral components of total hip replacements in response to an anteriorly applied load. Eng Med  vol. 17, (3) 127-129. 10.1243/EMED_JOUR_1988_017_033_02

Tanner KE, Reed PE, Bonfield W, Rasmussen GL and Freeman MA (1988). A system for modelling forces on the hip joint in one-legged stance. J Biomed Eng  vol. 10, (3) 289-290. 10.1016/0141-5425(88)90014-3

1985

Churches AE, Tanner KE and Harris JD (1985). An engineering evaluation of the Oxford External Fixator with sliding clamps: fixator stiffness and fracture healing assessment. Eng Med  vol. 14, (1) 21-29. 10.1243/EMED_JOUR_1985_014_005_02

Churches AE, Tanner KE, Evans M and Gwillim J (1985). Fracture healing assessment with external fixation. Eng Med  vol. 14, (1) 13-29. 10.1243/EMED_JOUR_1985_014_004_02

Churches AE, Tanner KE and Harris JD (1985). The Oxford External Fixator: fixator stiffness and the effects of bone pin loosening. Eng Med  vol. 14, (1) 3-29. 10.1243/EMED_JOUR_1985_014_003_02

1984

Harris JD, Kenwright J, Evans M, Tanner KE and Gwillim J (1984). Control of movement and fracture stiffness monitoring with external fixation. Orthopedics  vol. 7, (3) 485-490. 10.3928/0147-7447-19840301-15

1979

Evans M, Kenwright J and Tanner KE (1979). Analysis of single-sided external fracture fixation. Engineering in Medicine  vol. 8, (3) 133-137. 10.1243/EMED_JOUR_1979_008_036_02

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