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Institute of Bioengineering

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Biomechanics and Mechanobiology

Queen Mary University of London has a long standing, internationally-leading track record in 'biomechanics and mechanobiology'. This multidisciplinary research area examines the biomechanics of implantable biomaterials and devices as well as the biomechanics of biological systems at a range of length scales from whole body biomechanics to cell and tissue mechanics to protein nanomechanics, Our mechanobiology research explores the biological response to biomechanical, topographical or physico-chemical stimuli and the fundamental mechanotransduction mechanisms. The research brings together bioengineers with clinicians, modelers and biologists leading towards exciting translational impact in diagnosis and treatment of disease and injury.

Selected Expertise

Selected Applications

Selected Publications

  • Gait analysis and whole body biomechanics
  • Tissue / biomaterial biomechanics
  • Cell mechanics (Atomic Force Microscopy, pipette aspiration)
  • Nano mechanics (small angle Xray scattering)
  • Implant wear characterisation
  • Computational biomechanics modelling
  • Mechanobiology and mechanotransduction
  • Mechanical stimulation of cells
  • Nanotopography
  • Microscopy (super resolution, confocal, live cell)
  • Osteoarthritis, inflammation, tendinopathy, cardiovascular disease and cancer. 
  • Cartilage, bone, tendon, epithelial cells, fibroblasts, neurons, cancer cells and stem cells 
  • Whole body biomechanics and musculoskeletal disorders
  • Biomechanics of novel implantable biomaterials, devices and tissue engineered products.
  • Orthopaedic implant biomechanics and wear characteristics
  • Electrostimulated polymer systems to mimic muscle biomechanics
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